Bibliographie - 815 - Stabilis 4.0

References 815

Type :

Journal

Web link :

http://www.ajhp.org/cgi/content/abstract/55/24/2630

Research teams :

Athens - University of Georgia, College of Pharmacy

Authors :

Stewart JT, Warren FW, King DT, Venkateshwaran TG, Fox JL.

Title :

Stability of ondansetron hydrochloride and 12 medications in plastic syringes.

Reference :

Am J Health-Syst Pharm ; 55: 2630-2634. 1998

Level of Evidence :

Physical stability :

Chemical stability :

High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)

Stability defined as 95% of the initial concentration

Other methods :

Comments :

Stability indicating capability inadequately assessed

List of drugs

Alfentanil hydrochloride

167 µg/ml

Ondansetron hydrochloride

1.33 mg/ml

Atropine sulfate

0.133 mg/ml

Ondansetron hydrochloride

1.33 mg/ml

Droperidol

1.25 mg/ml

Ondansetron hydrochloride

1 mg/ml

Fentanyl citrate

16.7 µg/ml

Ondansetron hydrochloride

1.33 mg/ml

Glycopyrronium bromide

0.1 mg/ml

Ondansetron hydrochloride

1 mg/ml

Metoclopramide hydrochloride

2.5 mg/ml

Ondansetron hydrochloride

1 mg/ml

Midazolam hydrochloride

1.66 mg/ml

Ondansetron hydrochloride

1.33 mg/ml

Morphine sulfate

2.67 mg/ml

Ondansetron hydrochloride

1.33 mg/ml

Naloxone hydrochloride

0.133 mg/ml

Ondansetron hydrochloride

1.33 mg/ml

Neostigmine methylsulfate

0.167 mg/ml

Ondansetron hydrochloride

1.33 mg/ml

Ondansetron hydrochloride

1.33 mg/ml	+ Alfentanil hydrochloride	167 µg/ml	+
1.33 mg/ml	+ Atropine sulfate	0.133 mg/ml	+
1 mg/ml	+ Droperidol	1.25 mg/ml	+
1.33 mg/ml	+ Fentanyl citrate	16.7 µg/ml	+
1 mg/ml	+ Glycopyrronium bromide	0.1 mg/ml	+
1 mg/ml	+ Metoclopramide hydrochloride	2.5 mg/ml	+
1.33 mg/ml	+ Midazolam hydrochloride	1.66 mg/ml	+
1.33 mg/ml	+ Morphine sulfate	2.67 mg/ml	+
1.33 mg/ml	+ Naloxone hydrochloride	0.133 mg/ml	+
1.33 mg/ml	+ Neostigmine methylsulfate	0.167 mg/ml	+
1.33 mg/ml	+ Pethidine hydrochloride	8.33 mg/ml	+
1 mg/ml	+ Propofol	1 & 5 mg/ml	+

Pethidine hydrochloride

8.33 mg/ml

Ondansetron hydrochloride

1.33 mg/ml

Propofol

1 & 5 mg/ml

Ondansetron hydrochloride

1 mg/ml

23°C

Neostigmine methylsulfate	0.167 mg/ml
Ondansetron hydrochloride	1,33 mg/ml

23°C

Ondansetron hydrochloride	1,33 mg/ml
Naloxone hydrochloride	0,133 mg/ml

23°C

Ondansetron hydrochloride	1,33 mg/ml
Midazolam hydrochloride	1,66 mg/ml

23°C

Ondansetron hydrochloride	1,33 mg/ml
Alfentanil hydrochloride	167 µg/ml

23°C

Ondansetron hydrochloride	1,33 mg/ml
Atropine sulfate	0,133 mg/ml

23°C

Ondansetron hydrochloride	1,33 mg/ml
Morphine sulfate	2,67 mg/ml

23°C

Ondansetron hydrochloride	1,33 mg/ml
Pethidine hydrochloride	8,33 mg/ml

23°C

Ondansetron hydrochloride	1 mg/ml
Propofol	1 & 5 mg/ml

23°C

Ondansetron hydrochloride	1 mg/ml
Glycopyrronium bromide	0,1 mg/ml

4°C

Ondansetron hydrochloride	1,33 mg/ml
Naloxone hydrochloride	0,133 mg/ml

4°C

Midazolam hydrochloride	1,66 mg/ml
Ondansetron hydrochloride	1,33 mg/ml

4°C

Ondansetron hydrochloride	1,33 mg/ml
Alfentanil hydrochloride	167 µg/ml

4°C

Ondansetron hydrochloride	1,33 mg/ml
Atropine sulfate	0,133 mg/ml

4°C

Ondansetron hydrochloride	1,33 mg/ml
Morphine sulfate	2,67 mg/ml

4°C

Ondansetron hydrochloride	1,33 mg/ml
Pethidine hydrochloride	8,33 mg/ml

4°C

Ondansetron hydrochloride	1 mg/ml
Glycopyrronium bromide	0,1 mg/ml

4°C

Neostigmine methylsulfate	0.167 mg/ml
Ondansetron hydrochloride	1,33 mg/ml

23°C

Droperidol	1,25 mg/ml
Ondansetron hydrochloride	1 mg/ml

23°C

Fentanyl citrate	16,7 µg/ml
Ondansetron hydrochloride	1,33 mg/ml

23°C

Metoclopramide hydrochloride	2,5 mg/ml
Ondansetron hydrochloride	1 mg/ml

4°C

Fentanyl citrate	16,7 µg/ml
Ondansetron hydrochloride	1,33 mg/ml

4°C

Metoclopramide hydrochloride	2,5 mg/ml
Ondansetron hydrochloride	1 mg/ml