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References   References 730  
Type : Journal
Research teams : Oklahoma City - University of Oklahoma Health Sciences Center, College of Pharmacy
Authors : Allen LV, Saul Levinson R, Phisutsinthop D.
Title : Compatibility of various admixtures with secondary additives at Y-injection site of intravenous administration sets.
Reference : Am J Hosp Pharm ; 34: 939-943. 1977
Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
injectionAminophylline Various
Compatible 25 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
Compatible 25 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
injectionAmpicillin sodium Antibiotic
Compatible 25 >> 135 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
Compatible 25 >> 135 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
injectionCalcium gluconate Electrolyte
Compatible 100 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
injectionCefalotin sodium Antibiotic
Compatible 200 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Compatible 200 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Compatible 4 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
injectionDiazepam Anxiolytic
Incompatible 5 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Incompatible 5 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
injectionDigoxin Cardiotonic
Compatible 250 µg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Compatible 250 µg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
injectionEthacrynate sodium Diuretic
Compatible 1 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Compatible 1 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
injectionInsulin Glucose-lowering
Compatible 40 UI/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Compatible 40 UI/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
injectionKanamycin sulfate Antibiotic
Compatible 250 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
Compatible 250 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
injectionLidocaine hydrochloride Local anesthetic
Compatible 20 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Compatible 20 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 40 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
Incompatible 40 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
injectionPenicillin G potassium Antibiotic
Compatible + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Compatible + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
injectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Incompatible 50 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 40 mEq/l + injectionAminophylline 25 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionAminophylline 25 mg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionAmpicillin sodium 25 >> 135 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionAmpicillin sodium 25 >> 135 mg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionCalcium gluconate 100 mg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionCefalotin sodium 200 mg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionCefalotin sodium 200 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionDexamethasone sodium phosphate 4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionDexamethasone sodium phosphate 4 mg/ml + Ringer’s lactate solution
Incompatible 40 mEq/l + injectionDiazepam 5 mg/ml + Ringer’s lactate solution
Incompatible 40 mEq/l + injectionDiazepam 5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionDigoxin 250 µg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionDigoxin 250 µg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionEthacrynate sodium 1 mg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionEthacrynate sodium 1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionInsulin 40 UI/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionInsulin 40 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionKanamycin sulfate 250 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionKanamycin sulfate 250 mg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionLidocaine hydrochloride 20 mg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionLidocaine hydrochloride 20 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 40 mEq/l + injectionMethylprednisolone sodium succinate 40 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 40 mEq/l + injectionMethylprednisolone sodium succinate 40 mg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionPenicillin G potassium + Ringer’s lactate solution
Compatible 40 mEq/l + injectionPenicillin G potassium + NaCl 0,9% or Glucose 5%
Incompatible 40 mEq/l + injectionPhenytoin sodium 50 mg/ml + Ringer’s lactate solution
Incompatible 40 mEq/l + injectionPhenytoin sodium 50 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mEq/l + injectionSodium bicarbonate 75 mg/ml + Ringer’s lactate solution
Compatible 40 mEq/l + injectionSodium bicarbonate 75 mg/ml + NaCl 0,9% or Glucose 5%
injectionSodium bicarbonate Electrolyte
Compatible 75 mg/ml + injectionPotassium chloride 40 mEq/l + Ringer’s lactate solution
Compatible 75 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
  Mentions Légales