Last update :
18/07/2024
References   References 62  
Type : Journal

Research teams : Charlottesville - University of Virginia Health Sciences Center, Department of Pharmacy
Authors : Pugh CB, Pabis DJ, Rodriguez C.
Title : Visual compatibility of morphine sulfate and meperidine hydrochloride with other injectable drugs during simulated Y-site injection.
Reference : Am J Hosp Pharm ; 48: 123-125. 1991

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionAciclovir sodium Antiviral
Incompatible 5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionAtenolol Beta-blocker
Compatible 0.5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionAztreonam Antibiotic
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionBumetanide Diuretic
Compatible 0.25 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.25 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCeftazidime Antibiotic
Compatible 20 & 40 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 & 40 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCeftriaxone disodium Antibiotic
Compatible 20 & 40 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 & 40 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 0.2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionDigoxin Cardiotonic
Compatible 250 µg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 250 µg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 1&50 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 1 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 1.6 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1.6 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionDroperidol Neuroleptic
Compatible 2.5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionFamotidine Antihistamine (H2)
Compatible 0.2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionFluconazole Antifungal
Compatible 1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionFurosemide Diuretic
Incompatible 0.8 >> 10 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 2.4 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 2 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionImipenem - cilastatin sodium Antibiotic
Incompatible 5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionLabetalol hydrochloride Beta-blocker
Compatible 5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionLidocaine hydrochloride Local anesthetic
Compatible 1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 2.5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 2.5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionMetoclopramide hydrochloride Antiemetic
Compatible 0.2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionMetoprolol tartrate Anti-arrhythmic
Compatible 1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 1 mg/ml + Parenteral nutrition (binary mixture)
Incompatible 1 mg/ml + injectionAciclovir sodium 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionAtenolol 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionAztreonam 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionBumetanide 0.25 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCeftazidime 20 & 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCeftriaxone disodium 20 & 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDexamethasone sodium phosphate 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDigoxin 250 µg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDopamine hydrochloride 1.6 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionFamotidine 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionFluconazole 1 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionFurosemide 0.8 >> 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionLidocaine hydrochloride 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMethylprednisolone sodium succinate 2.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMetoclopramide hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMetoprolol tartrate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPropranolol hydrochloride 1 mg/ml + Glucose 5%
injectionPethidine hydrochloride Analgesic
Compatible 10 mg/ml + Parenteral nutrition (binary mixture)
Incompatible 10 mg/ml + injectionAciclovir sodium 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionAtenolol 0.5 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionAztreonam 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionBumetanide 0.25 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCeftazidime 20 & 40 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCeftriaxone disodium 20 & 40 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDexamethasone sodium phosphate 0.2 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDigoxin 250 µg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDiphenhydramine hydrochloride 1&50 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDobutamine hydrochloride 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDopamine hydrochloride 1.6 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDroperidol 2.5 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionFamotidine 0.2 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionFluconazole 1 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionFurosemide 2.4 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionFurosemide 10 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionFurosemide 0.8 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionHydrocortisone sodium succinate 2 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionImipenem - cilastatin sodium 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionLidocaine hydrochloride 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionMethylprednisolone sodium succinate 2.5 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionMetoclopramide hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionMetoprolol tartrate 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionPotassium chloride 400 mEq/l + Glucose 5%
Compatible 10 mg/ml + injectionPropranolol hydrochloride 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionVerapamil hydrochloride 2.5 mg/ml + Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 400 mEq/l + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionPropranolol hydrochloride Beta-blocker
Compatible 1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionVerapamil hydrochloride Anti-arrhythmic
Compatible 2.5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%

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