Last update :
14/12/2024
References   References 4521  
Type : Journal
Web link : https://doi.org/10.1515/pthp-2020-0011

Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Polo C, D’Huart E, Lesperlette G, Vigneron J, Meyer F, Demoré B.
Title : Compatibility of injectable posaconazole with drugs commonly used in a hematology care unit.
Reference : Pharmaceutical Technology in Hospital Pharmacy 2020

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAciclovir sodium Antiviral
Incompatible 3,5 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionAlizapride hydrochloride Antiemetic
Incompatible 3 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionCefepime dihydrochloride Antibiotic
Incompatible 40 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionFilgrastim Various
Compatible 3 µg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionFurosemide Diuretic
Incompatible 0,8 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionGanciclovir sodium Antiviral
Incompatible 3,5 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionInsulin aspart Glucose-lowering
Incompatible 100 UI/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionLevetiracetam Antiepileptic
Incompatible 5 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 20 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
Incompatible 0,4 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionMetoclopramide hydrochloride Antiemetic
Incompatible 0,1 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionNefopam Analgesic
Incompatible 2,5 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
Incompatible 0,2 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionOndansetron hydrochloride Antiemetic
Incompatible 0,48 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
Incompatible 0,14 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionPantoprazole sodium Proton pump inhibitor
Incompatible 0,4 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionParacetamol Analgesic
Incompatible 10 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionPhloroglucinol  Antispasmodic
Incompatible 0,8 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionPiperacillin sodium / tazobactam Antibiotic
Incompatible 160 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionPosaconazole Antifungal
Incompatible 1,2 mg/ml + injectionAciclovir sodium 3,5 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionAlizapride hydrochloride 3 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionCefepime dihydrochloride 40 mg/ml + Sodium chloride 0,9%
Compatible 1,2 mg/ml + injectionFilgrastim 3 µg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionFurosemide 0,8 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionGanciclovir sodium 3,5 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionInsulin aspart 100 UI/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionLevetiracetam 5 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionMethylprednisolone sodium succinate 20 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionMethylprednisolone sodium succinate 0,4 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionMetoclopramide hydrochloride 0,1 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionNefopam 2,5 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionNefopam 0,2 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionOndansetron hydrochloride 0,48 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionOndansetron hydrochloride 0,14 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionPantoprazole sodium 0,4 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionParacetamol 10 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionPhloroglucinol 0,8 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionPiperacillin sodium / tazobactam 160 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionPotassium chloride 1341 mEq/l + Sodium chloride 0,9%
Compatible 1,2 mg/ml + injectionTacrolimus 3 µg/ml + Sodium chloride 0,9%
Compatible 1,2 mg/ml + injectionTacrolimus 30 µg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + injectionTramadol hydrochloride 0,5 mg/ml + Sodium chloride 0,9%
injectionPotassium chloride Electrolyte
Incompatible 1341 mEq/l + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionTacrolimus Immunosuppressant
Compatible 3 µg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
Compatible 30 µg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
injectionTramadol hydrochloride Analgesic
Incompatible 0,5 mg/ml + injectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%

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