Last update :
19/11/2024
References   References 3948  
Type : Journal
Web link : http://journals.sagepub.com/doi/full/10.1177/0148607112464239

Research teams : Geneva - University Hospital of Geneva
Authors : Bouchoud L, Fonzo-Christe C, Klingm?ller M, Bonnabry P .
Title : Compatibility of Intravenous Medications With Parenteral Nutrition - In Vitro Evaluation.
Reference : JPEN ;30. 416?424. 2012

Level of Evidence : 
Physical stability : 
Particle counting 
Chemical stability : 
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionAmoxicillin sodium / clavulanic acid Antibiotic
Incompatible 50/10 mg/ml + Parenteral nutrition (with lipids)
Incompatible 50/10 mg/ml + Parenteral nutrition (binary mixture)
injectionCalcium chloride Electrolyte
Compatible 14.5 mg/ml + Parenteral nutrition (with lipids)
Compatible 14.5 mg/ml + Parenteral nutrition (binary mixture)
injectionCefepime dihydrochloride Antibiotic
Incompatible 100 mg/ml + Parenteral nutrition (binary mixture)
Incompatible 100 mg/ml + Parenteral nutrition (with lipids)
injectionCiclosporin Immunosuppressant
Compatible 2.5 mg/ml + Parenteral nutrition (binary mixture)
Compatible 2.5 mg/ml + Parenteral nutrition (with lipids)
injectionEsomeprazole sodium Proton pump inhibitor
Incompatible 0.8 mg/ml + Parenteral nutrition (binary mixture)
Incompatible 0,8 mg/ml + Parenteral nutrition (with lipids)
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + Parenteral nutrition (with lipids)
Compatible 50 µg/ml + Parenteral nutrition (binary mixture)
injectionFluorouracil Anticancer drug
Compatible < 12.5 mg/ml + Parenteral nutrition (with lipids)
Incompatible 25 & 50 mg/ml + Parenteral nutrition (with lipids)
Incompatible 25 & 50 mg/ml + Parenteral nutrition (with lipids)
Compatible < 12.5 mg/ml + Parenteral nutrition (binary mixture)
injectionFurosemide Diuretic
Compatible 10 mg/ml + Parenteral nutrition (binary mixture)
Compatible 10 mg/ml + Parenteral nutrition (with lipids)
injectionHuman albumin Various
Compatible 200 mg/ml + Parenteral nutrition (binary mixture)
Incompatible 200 mg/ml + Parenteral nutrition (with lipids)
injectionMagnesium sulfate Electrolyte
Compatible 48.1 mg/ml + Parenteral nutrition (binary mixture)
Compatible 48.1 mg/ml + Parenteral nutrition (with lipids)
injectionMeropenem Antibiotic
Compatible 50 mg/ml + Parenteral nutrition (binary mixture)
Compatible 50 mg/ml + Parenteral nutrition (with lipids)
injectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + Parenteral nutrition (binary mixture)
Compatible 5 mg/ml + Parenteral nutrition (with lipids)
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + Parenteral nutrition (binary mixture)
Compatible 5 mg/ml + Parenteral nutrition (with lipids)
injectionMidazolam hydrochloride Anxiolytic
Compatible 2.5 mg/ml + Parenteral nutrition (binary mixture)
Compatible 2.5 mg/ml + Parenteral nutrition (with lipids)
injectionMorphine sulfate Analgesic
Compatible 5 mg/ml + Parenteral nutrition (binary mixture)
Compatible 5 mg/ml + Parenteral nutrition (with lipids)
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 1 mg/ml + Parenteral nutrition (with lipids)
Compatible 1 mg/ml + Parenteral nutrition (binary mixture)
injectionOctreotide acetate Various
Compatible 0.025 mg/ml + Parenteral nutrition (binary mixture)
Compatible 0.025 mg/ml + Parenteral nutrition (with lipids)
injectionOndansetron hydrochloride Antiemetic
Compatible 2 mg/ml + Parenteral nutrition (binary mixture)
Compatible 2 mg/ml + Parenteral nutrition (with lipids)
injectionPantoprazole sodium Proton pump inhibitor
Incompatible 0.8 mg/ml + Parenteral nutrition (binary mixture)
Incompatible 0,8 mg/ml + Parenteral nutrition (with lipids)
injectionParacetamol Analgesic
Compatible 10 mg/ml + Parenteral nutrition (binary mixture)
Compatible 10 mg/ml + Parenteral nutrition (with lipids)
injectionPiperacillin sodium / tazobactam Antibiotic
Compatible 80 mg/ml + Parenteral nutrition (binary mixture)
Compatible 80 mg/ml + Parenteral nutrition (with lipids)
injectionPotassium phosphate Electrolyte
Compatible 0.00012 mmol/ml + Parenteral nutrition (binary mixture)
Compatible 0.00012 mmol/ml + Parenteral nutrition (with lipids)
injectionTacrolimus Immunosuppressant
Compatible 100 µg/ml + Parenteral nutrition (binary mixture)
Compatible 100 µg/ml + Parenteral nutrition (with lipids)
injectionTropisetron hydrochloride Antiemetic
Incompatible 1 mg/ml + Parenteral nutrition (with lipids)
Compatible 1 mg/ml + Parenteral nutrition (binary mixture)
injectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + Parenteral nutrition (with lipids)
Compatible 10 mg/ml + Parenteral nutrition (binary mixture)

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