| Type : |
Journal |
|
| Forskerteamet : |
Tolède - College of Pharmacy and Pharmaceutical Sciences, The University of Toledo |
| Forfattere : |
Alexander KS, Sundar S, White DB, Dollimore D. |
| Tittel : |
The Formulation Development and Stability of Spironolactone Suspension |
| Nummer : |
Int J Pharm Compound ; 1, 3: 195-199. 1997 |
|
| Nivå of Evidence : |
|
| fysisk stabilitet : |
|
| kjemisk stabilitet : |
|
| andre metoder : |
|
| Kommentarer : |
|
Lister
 Spironolactone
|
 |
 |
pH |
pH 4.5 |
 |
 |
 |
 |
 |
600 mg
®= ? |
| Karboksymetylcellulose |
900 mg |
| Veegum® |
900 mg |
| Metylparaben |
120 mg |
| Propylparaben |
24 mg |
| Propylenglykol |
1.2 ml |
| Sorbitol |
70% 48 ml |
| Natriumacetat |
350 mg |
| Eddiksyre |
36% 0.67 ml |
| Natriumbisulfitt |
120 mg |
| Natriumedetat |
120 mg |
| Natriumsakkarin |
24 mg |
| Ananasaroma |
|
| Destillert vann |
>> 120 ml |
|
30°C |
 |
| 90 |
 |
|
|
|
|
|
600 mg
®= ? |
| Karboksymetylcellulose |
900 mg |
| Veegum® |
900 mg |
| Metylparaben |
120 mg |
| Propylparaben |
24 mg |
| Propylenglykol |
1.2 ml |
| Sorbitol |
70% 48 ml |
| Natriumacetat |
350 mg |
| Eddiksyre |
36% 0.67 ml |
| Natriumbisulfitt |
120 mg |
| Natriumedetat |
120 mg |
| Natriumsakkarin |
24 mg |
| Ananasaroma |
|
| Destillert vann |
>> 120 ml |
|
5°C |
|
| 90 |
|
|
|
|
|
