| type : |
Artikel |
|
| onderzoeksgroepen : |
Tolède - College of Pharmacy and Pharmaceutical Sciences, The University of Toledo |
| Auteur : |
Alexander KS, Sundar S, White DB, Dollimore D. |
| titel : |
The Formulation Development and Stability of Spironolactone Suspension |
| Nummer : |
Int J Pharm Compound ; 1, 3: 195-199. 1997 |
|
| Niveau van bewijs : |
|
| fysische stabiliteit : |
|
| chemische stabiliteit : |
|
| andere methoden : |
|
| Reacties : |
|
Stoffenlijst
 Spironolactone
|
 |
 |
pH |
pH 4.5 |
 |
 |
 |
 |
 |
600 mg
®= ? |
| carboxymethylcellulose |
900 mg |
| Veegum® |
900 mg |
| methylparaben |
120 mg |
| propylparabeen |
24 mg |
| Propyleenglycol |
1.2 ml |
| sorbitol |
70% 48 ml |
| natriumacetaat |
350 mg |
| azijnzuur |
36% 0.67 ml |
| natriumbisulfiet |
120 mg |
| natrium edetaat |
120 mg |
| Natriumsacharine |
24 mg |
| ananas aroma |
|
| gedestilleerd water |
>> 120 ml |
|
30°C |
 |
| 90 |
 |
|
|
|
|
|
600 mg
®= ? |
| carboxymethylcellulose |
900 mg |
| Veegum® |
900 mg |
| methylparaben |
120 mg |
| propylparabeen |
24 mg |
| Propyleenglycol |
1.2 ml |
| sorbitol |
70% 48 ml |
| natriumacetaat |
350 mg |
| azijnzuur |
36% 0.67 ml |
| natriumbisulfiet |
120 mg |
| natrium edetaat |
120 mg |
| Natriumsacharine |
24 mg |
| ananas aroma |
|
| gedestilleerd water |
>> 120 ml |
|
5°C |
|
| 90 |
|
|
|
|
|
