| Type : |
Journal |
| Web link : |
http://www.ajhp.org/cgi/content/abstract/43/11/2803 |
|
| Research teams : |
West Point - Merck and Co |
| Authors : |
Bigley FP, Forsyth RJ, Henley MW. |
| Title : |
Compatibility of imipenem-cilastatin sodium with commonly used intravenous solutions. |
| Reference : |
Am J Hosp Pharm ; 43: 2803-2809. 1986 |
|
| Level of Evidence : |
|
| Physical stability : |
|
| Chemical stability : |
|
| Other methods : |
|
| Comments : |
| Degradation products not observed in real conditions | | Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point |
|
List of drugs
 Imipenem - cilastatin sodium
|
 |
 |
 |
 |
 |
 |
|
 |
-20°C |
|
|
|
 |
 |
|
 |
 |
 |
 |
2.5 mg/ml |
4°C |
 |
| 72 |
 |
|
|
|
|
|
2.5 & 5 mg/ml |
25°C |
 |
| 9 |
|
|
|
|
|
|
5 mg/ml |
4°C |
|
| 48 |
|
|
|
|
|
 |
2.5 mg/ml |
4°C |
|
| 72 |
|
|
|
|
|
|
2.5 & 5 mg/ml |
25°C |
|
| 9 |
|
|
|
|
|
|
5 mg/ml |
4°C |
|
| 48 |
|
|
|
|
|
 |
2.5 mg/ml |
25°C |
|
| 6 |
|
|
|
|
|
|
2.5 & 5 mg/ml |
4°C |
|
| 24 |
|
|
|
|
|
|
5 mg/ml |
25°C |
|
| 3 |
|
|
|
|
|
 |
2.5 mg/ml |
25°C |
|
| 6 |
|
|
|
|
|
|
2.5 & 5 mg/ml |
4°C |
|
| 24 |
|
|
|
|
|
|
5 mg/ml |
25°C |
|
| 3 |
|
|
|
|
|
 |
2.5 & 5 mg/ml |
25°C |
|
| 3 |
|
|
|
|
|
|
2.5 & 5 mg/ml |
4°C |
|
| 24 |
|
|
|
|
250 & 500 mg/ml |
+ Sodium bicarbonate
|
50 mg/ml |
| |
|
|
|
| |
+
|
|
|
|
Sodium bicarbonate
|
 |
|
|
