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References 1937
Type :
Journal
Web link :
https://doi.org/10.1345/aph.1E124
Research teams :
Lexington - Cubist Pharmaceuticals
Authors :
Lai JJ, Brodeur SK.
Title :
Physical and chemical stability of daptomycin with nine medications.
Reference :
Ann Pharmacotherapy ; 38: 1612-1616. 2004
Level of Evidence :
Physical stability :
Chemical stability :
Other methods :
Comments :
Changes in pH not commented or difficult to interpret
Degradation products not observed in real conditions
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Method not shown but the article refers to a validated method
List of drugs
Aztreonam
16,7 mg/ml
+
Daptomycin
16,7 mg/ml
+
Ceftazidime
16,7 mg/ml
+
Daptomycin
16,7 mg/ml
+
Ceftriaxone disodium
16,7 mg/ml
+
Daptomycin
16,7 mg/ml
+
Daptomycin
16,7 mg/ml
+
Aztreonam
16,7 mg/ml
+
16,7 mg/ml
+
Ceftazidime
16,7 mg/ml
+
16,7 mg/ml
+
Ceftriaxone disodium
16,7 mg/ml
+
18,2 mg/ml
+
Dopamine hydrochloride
3,6 mg/ml
+
6,3 mg/ml
+
Fluconazole
1,3 mg/ml
+
19,2 mg/ml
+
Gentamicin sulfate
1,5 mg/ml
+
19,6 mg/ml
+
Heparin sodium
98 UI/ml
+
14,3 mg/ml
+
Levofloxacine
7,1 mg/ml
+
16,7 mg/ml
+
Lidocaine hydrochloride
3,3 mg/ml
+
Dopamine hydrochloride
3,6 mg/ml
+
Daptomycin
18,2 mg/ml
+
Fluconazole
1,3 mg/ml
+
Daptomycin
6,3 mg/ml
+
Gentamicin sulfate
1,5 mg/ml
+
Daptomycin
19,2 mg/ml
+
Heparin sodium
98 UI/ml
+
Daptomycin
19,6 mg/ml
+
Levofloxacine
7,1 mg/ml
+
Daptomycin
14,3 mg/ml
+
Lidocaine hydrochloride
3,3 mg/ml
+
Daptomycin
16,7 mg/ml
+
22°C-28°C
Daptomycin
16,7 mg/ml
Aztreonam
16,7 mg/ml
2
22°C-28°C
Daptomycin
16,7 mg/ml
Ceftazidime
16,7 mg/ml
2
22°C-28°C
Daptomycin
16,7 mg/ml
Ceftriaxone disodium
16,7 mg/ml
2
22°C-28°C
Daptomycin
16,7 mg/ml
Lidocaine hydrochloride
3,3 mg/ml
2
22°C-28°C
Daptomycin
18,2 mg/ml
Dopamine hydrochloride
3,6 mg/ml
2
22°C-28°C
Daptomycin
19,2 mg/ml
Gentamicin sulfate
1,5 mg/ml
2
22°C-28°C
Daptomycin
6,3 mg/ml
Fluconazole
1,3 mg/ml
2
22°C-28°C
Daptomycin
19,6 mg/ml
Heparin sodium
5000 UI/ml
2
22°C-28°C
Daptomycin
14,3 mg/ml
Levofloxacine
7,1 mg/ml
2
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