Last update :
14/12/2024
Anticancer drug   Etoposide  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Eposin Belgium, Colombia, Great Britain, Malaysia, Norway, Republic of South Africa, Sweden
Etocris Argentina, Chile, Peru
Etolon India
Etomedac Germany, Luxembourg
Etonolver Venezuela
Etoposide France, Greece, Netherlands
Etosid Egypt, India, Malaysia
Eunades Brazil
Euvaxon Argentina
Exitop Finland, Germany, Sweden
Fytosid Egypt, India, Malaysia
Lastet Egypt, Hungary, Iran, Italy, Poland, Turkey, United Arab Emirates
Onkoposid Germany
Riboposid Germany
Sedol Peru
Toposin Netherlands
Tosuben Mexico
Vepesid Australia, Austria, Belgium, Canada, Colombia, Croatia, Denmark, Egypt, Finland, Germany, Greece, Hungary, Ireland, Italy, Luxembourg, Netherlands, Poland, Republic of South Africa, Saudi Arabia, Slovenia, Spain, Switzerland, Turkey, United States of America
Vepeside Morocco, Tunisia
Compatibility   injection   Compatibility : Etoposide              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Etoposide 0.4 mg/ml
injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
injection Etoposide 0.4 mg/ml
injection Amifostine 10 mg/ml
Glucose 5% 3
Compatible
injection Etoposide 0.4 mg/ml
injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
injection Etoposide 0,2 & 0,4 mg/ml
injection Cisplatin 0,2 mg/ml
Sodium chloride 0,9% 417
Compatible
injection Etoposide 0,2 & 0,4 mg/ml
injection Cisplatin 0,2 mg/ml
NaCl 0,45% Glucose 5% 417
Compatible
injection Etoposide 0.4 mg/ml
injection Cladribine 0.015 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Etoposide 0.4 mg/ml
injection Cladribine 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Etoposide 0.4 mg/ml
injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Immediate precipitation Incompatible
injection Etoposide 0.4 mg/ml
injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
injection Etoposide 0.4 mg/ml
injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Precipitation after 1 hour Incompatible
injection Etoposide 0.4 mg/ml
injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Compatible
injection Etoposide 0.4 mg/ml
injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Etoposide 0.4 mg/ml
injection Granisetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 57
Compatible
injection Etoposide 0.4 mg/ml
injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
injection Etoposide 1 mg/ml
injection Hydroxyzine dihydrochloride 0.5 mg/ml
Glucose 5% 331
Production of gas bubbles Incompatible
injection Etoposide 0.4 mg/ml
injection Idarubicin hydrochloride 1 mg/ml
Sodium chloride 0,9% 491
Compatible
injection Etoposide 0.4 mg/ml
injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
injection Etoposide 0.6 mg/ml
injection Methotrexate sodium 30 mg/ml
Sodium chloride 0,9% 150
Compatible
injection Etoposide 0.4 mg/ml
injection Micafungin 1.5 mg/ml
Sodium chloride 0,9% 2108
Compatible
injection Etoposide 0,5 & 10 mg/ml
injection Mitoxantrone dihydrochloride 0,05 & 1 mg/ml
Sodium chloride 0,9% 1730
Compatible
injection Etoposide 0,14 >> 0,25 mg/ml
injection Ondansetron hydrochloride 0,016 >> 0,16 mg/ml
3574
Compatible
injection Etoposide 0,1 mg/ml
injection Ondansetron hydrochloride 0,03 mg/ml
Glucose 5% 184
Compatible
injection Etoposide 0,4 mg/ml
injection Ondansetron hydrochloride 0,03 mg/ml
Glucose 5% 184
Compatible
injection Etoposide 0,4 mg/ml
injection Ondansetron hydrochloride 0,3 mg/ml
Glucose 5% 184
Compatible
injection Etoposide 0,1 mg/ml
injection Ondansetron hydrochloride 0,3 mg/ml
Glucose 5% 184
Compatible
injection Etoposide 0.4 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
injection Etoposide 0.4 mg/ml
injection Paclitaxel 1.2 mg/ml
Glucose 5% 85
Compatible
injection Etoposide 0.4 mg/ml
injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
injection Etoposide 0.4 mg/ml
injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
injection Etoposide 0.6 mg/ml
injection Sodium bicarbonate 14 mg/ml
None 150
Compatible
injection Etoposide 0.4 mg/ml
injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
injection Etoposide 0.4 mg/ml
injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
injection Etoposide 0.4 mg/ml
injection Topotecan 0.056 mg/ml
NaCl 0,9% or Glucose 5% 1026
Compatible
injection Etoposide 0.4 mg/ml
injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Compatible
injection Etoposide 0.6 mg/ml
NaHCO3 150

  Mentions Légales