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Cardiotonic   Dobutamine hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Cardiforce India
Cardiject India, Iran, Morocco
Dobcar Turkey
Dobine Chile
Dobucard Argentina
Dobucin Ecuador
Dobucor Spain
Dobuject Colombia, Egypt, Finland, Mexico, Poland, Saudi Arabia, Tunisia
Doburan Venezuela
Dobutabag Turkey
Dobutamex Iran
Dobutamin Austria, Germany, Hungary, Ireland, Norway, Poland
Dobutamina Argentina, Chile, Colombia, Ecuador, Italy, Mexico, Peru, Portugal, Spain
Dobutamine Belgium, Canada, Egypt, Great Britain, Ireland, Malaysia, Morocco, Poland, Tunisia, United States of America
Dobutrex Belgium, Colombia, Denmark, Great Britain, Ireland, Italy, Luxembourg, Mexico, Netherlands, Norway, Saudi Arabia, Spain, Sweden, Switzerland
Duvig Argentina
Endobil Chile
Inotop Austria
Inotrex Greece, Portugal
Insucard Brazil
Miozac Italy
Oxiken Mexico
Posiject Great Britain
Stability in solutions   injection   Stability in solutions : Dobutamine hydrochloride     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass NaCl 0,9% or Glucose 5% 0,25 mg/ml 5°C Protect from light
7 Day
1045
Level of evidence C
Glass NaCl 0,45% Glucose 5% 1 mg/ml 25°C Light
48 Hour
1058

Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,25 mg/ml 5°C Protect from light
7 Day
1045
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml 25°C Not specified
48 Hour
628
Level of evidence D
Polyvinyl chloride NaCl 0,9% or Glucose 5% 10 mg/ml 25°C Not specified
12 Hour
4141
Level of evidence A+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 10 mg/ml 35°C Not specified
12 Hour
4141
Level of evidence A+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 10 mg/ml 4°C Not specified
7 Day
4141
Level of evidence A+
Polyvinyl chloride Glucose 5% 1 & 5 mg/ml 5°C Protect from light
30 Day
197
Level of evidence D
Polyvinyl chloride Ringer’s lactate solution 1 mg/ml 25°C Not specified
48 Hour
628
Level of evidence D
Polyvinyl chloride NaCl 0,45% Glucose 5% 1 mg/ml 25°C Not specified
48 Hour
628
Level of evidence D
Polyvinyl chloride NaCl 0,45% Glucose 5% 1 mg/ml 25°C Light
48 Hour
1058

Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,0025 mg/ml 26°C Not specified
4 Hour
2371
Level of evidence B
Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,0025 mg/ml 4°C Not specified
24 Hour
2371
Level of evidence B
Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,005 mg/ml 26°C Not specified
24 Hour
2371
Level of evidence B
Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,005 mg/ml 37°C Not specified
24 Hour
2371
Level of evidence B
Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,005 mg/ml 4°C Not specified
24 Hour
2371
Level of evidence B
Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,0075 mg/ml 26°C Not specified
24 Hour
2371
Level of evidence B
Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,0075 mg/ml 37°C Not specified
24 Hour
2371
Level of evidence B
Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,0075 mg/ml 4°C Not specified
24 Hour
2371
Level of evidence B
Polyethylene NaCl 0,9% or Glucose 5% 0,5 mg/ml 22°C Protect from light
24 Hour
1067
Level of evidence C
Polyethylene NaCl 0,9% or Glucose 5% 0,5 mg/ml 4°C Protect from light
24 Hour
1067
Level of evidence C
Polypropylen Syringe NaCl 0,9% or Glucose 5% 10 mg/ml 2-8°C Protect from light
365 Day
4584
Level of evidence B+
Polypropylen Syringe Sodium chloride 0,9% 10 mg/ml -25 >> -15°C Protect from light
90 Day
4584
Level of evidence B+
Polypropylen Syringe Sodium chloride 0,9% 10 mg/ml 23-27°C Protect from light
30 Day
4584
Level of evidence B+
Polypropylen Syringe Glucose 5% 10 mg/ml -25 >> -15°C Protect from light
21 Day
4584
Level of evidence B+
Polypropylen Syringe Glucose 5% 10 mg/ml 20°C Protect from light
35 Day
3293
Level of evidence A
Polypropylen Syringe Glucose 5% 10 mg/ml 4°C Protect from light
42 Day
3293
Level of evidence A
Polypropylen Syringe Glucose 5% 5 mg/ml 23-25°C With or without light
48 Hour
206
Level of evidence C
Polypropylen Syringe Glucose 5% 5 mg/ml 25°C Light
24 Hour
196
Level of evidence D
Polypropylen Syringe Glucose 5% 5 mg/ml 4°C With or without light
48 Hour
206
Level of evidence C
AT-Closed vial® NaCl 0,9% or Glucose 5% 10 mg/ml -25 >> -15°C Protect from light
365 Day
4584
Level of evidence B+
AT-Closed vial® NaCl 0,9% or Glucose 5% 10 mg/ml 2-8°C Protect from light
365 Day
4584
Level of evidence B+
AT-Closed vial® NaCl 0,9% or Glucose 5% 10 mg/ml 23-27°C Protect from light
365 Day
4584
Level of evidence B+
Not specified Glucose 5% 4 mg/ml 23°C Protect from light
30 Day
1753
Level of evidence A
Not specified Glucose 5% 4 mg/ml 5°C Protect from light
30 Day
1753
Level of evidence A
  Mentions Légales