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Cardiotonic   Dobutamine hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Cardiforce India
Cardiject India, Iran, Morocco
Dobcar Turkey
Dobine Chile
Dobucard Argentina
Dobucin Ecuador
Dobucor Spain
Dobuject Colombia, Egypt, Finland, Mexico, Poland, Saudi Arabia, Tunisia
Doburan Venezuela
Dobutabag Turkey
Dobutamex Iran
Dobutamin Austria, Germany, Hungary, Ireland, Norway, Poland
Dobutamina Argentina, Chile, Colombia, Ecuador, Italy, Mexico, Peru, Portugal, Spain
Dobutamine Belgium, Canada, Egypt, Great Britain, Ireland, Malaysia, Morocco, Poland, Tunisia, United States of America
Dobutrex Belgium, Colombia, Denmark, Great Britain, Ireland, Italy, Luxembourg, Mexico, Netherlands, Norway, Saudi Arabia, Spain, Sweden, Switzerland
Duvig Argentina
Endobil Chile
Inotop Austria
Inotrex Greece, Portugal
Insucard Brazil
Miozac Italy
Oxiken Mexico
Posiject Great Britain
Stability of mixtures   injection   Stability of mixtures : Dobutamine hydrochloride     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass NaCl 0,9% or Glucose 5% 0,25 & 5 mg/ml
injection   Dobutamine hydrochloride   
injection   Tirofiban 50 µg/ml
20°C-25°C
4 Hour
Light 1603
Level of evidence A+
Glass NaCl 0,9% or Glucose 5% 0,25 mg/ml
injection   Dobutamine hydrochloride   
injection   Verapamil hydrochloride 0,16 mg/ml
5°C
7 Day
Protect from light 1045
Level of evidence C
Glass Sodium chloride 0,9% 2 mg/ml
injection   Dobutamine hydrochloride   
injection   Nitroprusside sodium 0,2 mg/ml
injection   Nitroglycerin 0,2 mg/ml
?
24 Hour
Not specified 1109
Glass Glucose 5% 2,5 mg/ml
injection   Dobutamine hydrochloride   
injection   Labetalol hydrochloride 1 mg/ml
20°C-25°C
4 Hour
Light 199
Level of evidence A
Glass Glucose 5% 5 mg/ml
injection   Dobutamine hydrochloride   
injection   Nitroprusside sodium 1,2 mg/ml
22°C
24 Hour
Protect from light 3381
Glass Glucose 5% 5 mg/ml
injection   Dobutamine hydrochloride   
injection   Norepinephrine bitartrate 0,06 mg/ml
22°C
24 Hour
3381
Glass Glucose 5% 5 mg/ml
injection   Dobutamine hydrochloride   
injection   Norepinephrine bitartrate 0,06 mg/ml
injection   Amiodarone hydrochloride 12,5 mg/ml
22°C
24 Hour
3381
Glass Glucose 5% 4 mg/ml
injection   Dobutamine hydrochloride   
injection   Milrinone lactate 0,2 mg/ml
22°C-23°C
4 Hour
Light 813
Level of evidence A
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml
injection   Dobutamine hydrochloride   
injection   Zidovudine 2 mg/ml
23°C
24 Hour
Light 1878
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml
injection   Dobutamine hydrochloride   
injection   Zidovudine 2 mg/ml
4°C
24 Hour
Not specified 1878
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,25 mg/ml
injection   Dobutamine hydrochloride   
injection   Verapamil hydrochloride 0,16 mg/ml
5°C
7 Day
Protect from light 1045
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,25 & 1 mg/ml
injection   Dobutamine hydrochloride   
injection   Ranitidine hydrochloride 0,05 & 2 mg/ml
?
48 Hour
Not specified 210
Level of evidence B
Polyvinyl chloride Glucose 5% 2 mg/ml
injection   Dobutamine hydrochloride   
injection   Flumazenil 0,02 mg/ml
23°C
24 Hour
Light 187
Level of evidence A
Polyethylene Glucose 5% 5 mg/ml
injection   Dobutamine hydrochloride   
injection   Nitroprusside sodium 1,2 mg/ml
22°C
24 Hour
Protect from light 3381
Polyethylene Glucose 5% 5 mg/ml
injection   Dobutamine hydrochloride   
injection   Norepinephrine bitartrate 0,06 mg/ml
22°C
24 Hour
3381
Polyethylene Glucose 5% 5 mg/ml
injection   Dobutamine hydrochloride   
injection   Norepinephrine bitartrate 0,06 mg/ml
injection   Amiodarone hydrochloride 12,5 mg/ml
22°C
24 Hour
3381
Polypropylene NaCl 0,9% or Glucose 5% 8 mg/ml
injection   Dobutamine hydrochloride   
injection   Dopamine hydrochloride 8 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
Polypropylene NaCl 0,9% or Glucose 5% 8 mg/ml
injection   Dobutamine hydrochloride   
injection   Methadone hydrochloride 0.2 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
Polypropylene Glucose 5% 8 mg/ml
injection   Dobutamine hydrochloride   
injection   Midazolam hydrochloride 4 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
  Mentions Légales