Monographie - Paracetamol

Last update :
19/11/2024

Paracetamol

Chemical structure

Tradename

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Apotel	Greece, Iran
Axapara	Ecuador
Eupifalgan	Egypt
Febrinil	India
Feveril	Ecuador
Flashmol	Chile
Imitimol	Chile
Injectmol	Egypt
Ofirmev	United States of America
Paraconica	Switzerland
Parasedol	Turkey
Parol	Turkey
Partemol	Turkey
Perfalgan	Austria, Denmark, Egypt, Finland, France, Germany, Great Britain, Iceland, Ireland, Italy, Netherlands, New Zealand, Norway, Poland, Portugal, Romania, Saudi Arabia, Spain, Sweden, Switzerland, Tunisia, Turkey, United Arab Emirates
Perfusalgan	Belgium, Luxembourg
Raziphemol	Belgium, Egypt, Luxembourg
Tempra	Mexico
Vedraphen	Egypt

References : Paracetamol

	Type	Publication
150	Journal	Aujoulat P, Coze C, Braguer D, Raybaud C. Physicochemical compatibility of methotrexate with co-administered drugs during cancer chemotherapy regimens. J Pharm Clin 1993 ; 12: 31-35.
2122	Journal	Kambia NK, Luyckx M, Dine T, Dupin-Sriet T, Gressier B, Brunet C. Stability and compatibility of paracetamol injection admixed with ketoprofen. EJHP Science 2006 ; 12, 4: 81-84.
2140	Journal	Kambia NK, Luyckx M, Dine T, Dupin-Spriet T, Gressier B, Brunet C. Stability and compatibility of the ready-to-use solution of paracetamol admixted with phloroglucinol for intravenous infusion. EJHP Science 2006 ; 12, 5: 91-95.
2231	Journal	de Jongh R, Hens R, Basma V, mouton JW, Tulkens PM, Carryn S. Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection. J Antimicrob Chemother 2008 ; 61, 2: 382-388.
3075	Journal	Balayssac D, Badaroux L, Rodier C, Sautou-Miranda V, Bazin JE, Chopineau J. Compatibility and stability of parenteral analgesic admixtures for multimodal analgesia EJHP Science 2009 ; 15, 4: 78-82.
3315	Poster	Louvrier M, Dhennain S, Hocahrt S, Zawadski E, Bouffart S, Moquay E. Mise en évidence d'une incompatibilité physico-chimique entre la phénytoïne sodique et le paracétamol injectable en flacon. Communication orale Hopipharm 2012
3350	Journal	Kwiatkowski J.L, Johnson C.E, Wagner D.S. Extended stability of intravenous acetaminophen in syringes and opened vials. Am J Health-Syst Pharm 2012 ; 69:1999-2001
3372	Journal	Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S. Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine. Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
3571	Journal	Anderson C, Boehme S, Ouellette J, Stidham C, MacKay M. Physical and Chemical Compatibility of Injectable Acetaminophen During Simulated Y-Site Administration. Hosp Pharm 2014 ; 49, 1: 42-47.
3728	Journal	Correard F, Savry A, Gauthier-Villano L, Pisano P, Pourroy B. Visual compatibility of defibrotide with selected drugs during simulated Y-site administration. Am J Health-Syst Pharm 2014 ; 71: 1288-1291.
3769	Manufacturer	Paracatamol (Paracetamol B Braun®) - Résumé des caractéristiques du produit B Braun laboratoire 2014
3824	Journal	Boudi S, Roy H, Forest JM, Leclair G. Compatibilité physique de l'association amoxicilline-acide clavulanique en injection avec plusieurs autres médicaments lors d'une administration en Y. Pharmactuel 2023 2023;56,3:91-98
3879	Journal	Foushee Jaime A, Meredith Pmichaele, Fox Laura M, Grace Edward E. Y-site Physical Compatibility of Beta-blocker Infusions with Intensive Care Unit Admixtures. Int J Pharm Compound 2016 ; 20, 4 : 328-332.
3948	Journal	Bouchoud L, Fonzo-Christe C, Klingm?ller M, Bonnabry P . Compatibility of Intravenous Medications With Parenteral Nutrition - In Vitro Evaluation. JPEN 2012 ;30. 416?424.
3967	Journal	Staven V, Herra I, Wang S, Grönlie I,Tho I. Physical compatibility of total parenteral nutrition and drugs in Y-site administration to children from neonates to adolescents. J Pharm Pharmacol 2017 ;69,7:448-462
3976	Journal	Du Repaire T, Vigne P, Guedon A, Gauthier-Villano L, Bertault Peres P, Pourroy B. Visual compatibility of blinatumomab with selected co-administrated drugs during simulated Y-site administration. Am J Health-Syst Pharm 2017 ; 74,16 : 1217-1218
3985	Poster	Manai M., Soussi M.A., Lazreg O., Drira C., Ben Tekaya S. et Razgallah Khrouf M. Compatibilité physique entre médicaments injectables et nutrition parentérale pédiatrique : Evaluation in-vitro. Hopipharm Congress 2017 - Nancy 2017
4362	Journal	Lopez Navarro AA, Martinez Gomez MA, Gras Colomer E, Campillos P, Climente Marti M. Physicochemical stability of binary admixtures of paracetamol and dexketoprofen-trometamol for patient-controlled analgesia use. EJHP 2018 Eur J Hosp Pharm 2018;0:1
4435	Journal	Hanifah S, Nugroho B.H, Chabib L. Compatibility of acetaminophen with central nervous system medications during simulated Y-site injection. Anaesthesiol Intensive Ther 2020 ; 52, 1: 23-27.
4465	Journal	Foushee A, Meredith P, Fox Laura, Wilder A. Y-site physical compatibility of hydrocortisone continuous infusions with admixtures used in critically ill patients. Am J Health-Syst Pharm 2020 ;77,14:1144-1148
4488	Journal	Nezvalova-Henriksen K, Niklas Nilsson N, Tomine Østerberg C, Staven Berge V, Tho I. Y-Site Physical Compatibility of Numeta G13E with Drugs Frequently Used at Neonatal Intensive Care. Pharmaceutics 2020 ; 12, 677.
4521	Journal	Polo C, D’Huart E, Lesperlette G, Vigneron J, Meyer F, Demoré B. Compatibility of injectable posaconazole with drugs commonly used in a hematology care unit. Pharmaceutical Technology in Hospital Pharmacy 2020
4543	Journal	Senarathna G, Strunk T, Petrovski M, Batty K. Physical compatibility of pentoxifylline and intravenous medications. Archives of Disease in Childhood 2018 ;104:292–295.
4642	Poster	Larossa garcia M, Jimenez-Lozano I, Boix-Montanés A, Mallandrich Miret M, Clemente Bautista M, cabanas Poy M.J., Gorgas Torner Compatibilidad en Y de atosiban y farmacois habitualmente utilizados en obstetricia. SEFH Congress (Virtual) October 2021 2021
4698	Journal	Ayari G, D'Huart E, Vigneron J, Demoré B. Y-site compatibility of intravenous medications commonly used in intensive care units : laboratory tests on 75 mixtures involving nine main drugs. Pharmaceutical Technology in Hospital Pharmacy 2022
4742	Journal	Macoviciuc M, Nguyen C, Forest J-M, Leclair G. Compatibilité physique de l’acétaminophène injectable avec 102 autres médicaments lors d’une administration en Y. Pharmactuel 2022 ; 55, 4: 247-255.
4837	Journal	De Silva, D.T.N Petrovski M, Strunk T, Mukadam N, Page‑Sharp N, Moore B.R, Batty K.T. Physicochemical compatibility of caffeine citrate and caffeine base injections with parenteral medications used in neonatal intensive care settings. Eur J Clin Pharmacol 2024 ; 80:1079–1087.
4842	Journal	Souha H Y, Alka G, Yunmei S, Nicole E W, Sanjay G. Harmonising IV Oxycodone with Paediatric Perioperative Medications: A Compatibility Study Through Y-Type Connectors Drug Design Dev Ther 2024 Drug Design, Development

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