Monographie - Papaverine hydrochloride - Stabilis 4.0

Last update :
19/11/2024

Vasodilator

Papaverine hydrochloride

injection

Stability in solutions

Stability of mixtures

Factors which affect stability

Compatibility

Route of administration

References

pdf

Chemical structure

Tradename

Tradename

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

DBL papaverine hydrochloride	New Zealand
Papaverin Recip	Sweden
Papaverine chlorhydrate	France, Malaysia

References

injection

References : Papaverine hydrochloride

	Type	Publication
456	Journal	Tu YH, Allen LV, Wang DP. Stability of papaverine hydrochloride and phentolamine mesylate in injectable mixtures. Am J Hosp Pharm 1987 ; 44: 2524-2527.
939	Journal	Gilbar PJ, Groves CF. Visual compatibility of total parenteral nutrition solution (Synthamin 17 Premix*) with selected drugs during simulated Y-site injection. Aust J Hosp Pharm 1994 ; 24: 167-170.
1085	Journal	Irving HD, Burbridge BE. Incompatibility of contrast agents with intravascular medications. Radiology 1989 ; 173: 91-92.
1899	Journal	Trissel LA, Zhang Y. Long-term stability of Trimix : a three drug injection used to treat rectile dysfunction. Int J Pharm Compound 2004 ; 8, 3: 231-235.
2150	Journal	Soli M, Bertaccini A, carparelli F, Gotti R, Cavrini V, Andrisano V, Martorana G. Vasoactive cocktails for erectile dysfunction: chemical stability of PGE1, papaverine and phentolamine. J Urology 1998 ; 160; 2: 551-555.
3448	Journal	Vieillard V, Eychenne N, Astier A, Yiou R, Deffaux C, Paul M. Physicochemical stability study of a new Trimix formulation for treatment of erectile dysfunction. Ann Pharm Fr 2013 ; 71, 5: 358-363.

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