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Antidote   Naloxone hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
DBL Naloxone Malaysia, New Zealand
Grayxona Argentina
Lefebre Mexico
Mapin Malaysia
Miniject Naloxone Great Britain
Naloxan Iran
Naloxon Belgium, Germany, Iceland, Norway, Sweden, Switzerland
Naloxona Argentina, Chile, Colombia, Spain
Naloxone Australia, Canada, Great Britain, Iran, Ireland, Italy, New Zealand, Saudi Arabia, Spain, United States of America
Naloxonum Poland
Narcan Australia, France, Great Britain, Greece, Ireland, Italy, Luxembourg, Netherlands, New Zealand, Switzerland, United States of America
Narcanti Austria, Chile, Denmark, Finland, Germany, Hungary, Sweden
Narcotan India
Narxona Argentina
Naxan Portugal
Naxone Saudi Arabia
Nexodal Norway, Romania, Spain, Sweden
Stability of mixtures   injection   Stability of mixtures : Naloxone hydrochloride     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass Sodium chloride 0,9% 0,004 mg/ml
injection   Naloxone hydrochloride   
injection   Fentanyl citrate 20 µg/ml
25°C
72 Hour
Protect from light 4559
Level of evidence A
Glass Sodium chloride 0,9% 0,004 mg/ml
injection   Naloxone hydrochloride   
injection   Fentanyl citrate 20 µg/ml
4°C
72 Hour
Protect from light 4559
Level of evidence A
Polyvinyl chloride Sodium chloride 0,9% 0.004 mg/ml
injection   Naloxone hydrochloride   
injection   Morphine sulfate 1 mg/ml
22°C
72 Hour
Not specified 3434
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 0,0125 mg/ml
injection   Naloxone hydrochloride   
injection   Morphine sulfate 1 mg/ml
22°C
72 Hour
Not specified 3434
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 0,025 mg/ml
injection   Naloxone hydrochloride   
injection   Morphine sulfate 1 mg/ml
22°C
72 Hour
Not specified 3434
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 0,004 mg/ml
injection   Naloxone hydrochloride   
injection   Fentanyl citrate 20 µg/ml
25°C
72 Hour
Protect from light 4559
Level of evidence A
Polyvinyl chloride Sodium chloride 0,9% 0,004 mg/ml
injection   Naloxone hydrochloride   
injection   Fentanyl citrate 20 µg/ml
4°C
72 Hour
Protect from light 4559
Level of evidence A
Polyvinyl chloride Sodium chloride 0,9% 0,025 mg/ml
injection   Naloxone hydrochloride   
injection   Morphine sulfate 1 mg/ml
4°C
30 Day
Not specified 3434
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 0,0125 mg/ml
injection   Naloxone hydrochloride   
injection   Morphine sulfate 1 mg/ml
4°C
30 Day
Not specified 3434
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 0,004 mg/ml
injection   Naloxone hydrochloride   
injection   Morphine sulfate 1 mg/ml
4°C
30 Day
Not specified 3434
Level of evidence D
Polypropylene Sodium chloride 0,9% 0,133 mg/ml
injection   Naloxone hydrochloride   
injection   Ondansetron hydrochloride 1,33 mg/ml
23°C
24 Hour
Light 815
Level of evidence C+
Polypropylene Sodium chloride 0,9% 0,133 mg/ml
injection   Naloxone hydrochloride   
injection   Ondansetron hydrochloride 1,33 mg/ml
4°C
24 Hour
Protect from light 815
Level of evidence C+
  Mentions Légales