Last update :
19/11/2024
Immunosuppressant   Tacrolimus  
injection
Eye-drops Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Prograf Australia, Austria, Canada, Chile, Colombia, Denmark, Finland, France, Germany, Great Britain, Greece, Hungary, Iran, Ireland, Italy, Japan, Malaysia, New Zealand, Norway, Poland, Portugal, Romania, Spain, Sweden, Switzerland, United States of America
Prograft Belgium, Luxembourg, Netherlands
Stability of mixtures   injection   Stability of mixtures : Tacrolimus     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass Sodium chloride 0,9% 10 µg/ml
injection   Tacrolimus   
injection   Cimetidine hydrochloride 0,6 mg/ml
22°C-26°C
48 Hour
Not specified 207
Glass Sodium chloride 0,9% 5 & 20 µg/ml
injection   Tacrolimus   
injection   Fluconazole 0,5 & 1,5 mg/ml
23°C-25°C
3 Hour
Light 1421
Level of evidence A
Glass Sodium chloride 0,9% 5 & 20 µg/ml
injection   Tacrolimus   
injection   Morphine sulfate 0,5 & 1,5 mg/ml
23°C-25°C
4 Hour
Light 814
Level of evidence A
Glass Glucose 5% 5 & 20 µg/ml
injection   Tacrolimus   
injection   Hydromorphone hydrochloride 0,1 & 1 mg/ml
23°C-25°C
4 Hour
Light 814
Level of evidence A
Glass Glucose 5% 5 & 20 µg/ml
injection   Tacrolimus   
injection   Ceftazidime 20 & 100 mg/ml
23°C-25°C
4 Hour
Light 814
Level of evidence A

  Mentions Légales