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19/11/2024
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Antibiotic   Vancomycin hydrochloride  
injection
Eye-drops Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Amplobac Brazil
Anco L IV Turkey
Celovan Brazil, India, Peru, Venezuela
Dhacocin Malaysia
Edicin Poland, Romania, Slovenia, Turkey
Estafimac Mexico
Estavam Mexico
Imvaco Chile
Kovan Chile
Rivervan Argentina
Tancofeto Colombia, Malaysia
Vacsol Mexico
Valcidem Mexico
Vamysin Belgium, Luxembourg
Vanaurus Colombia, Ecuador
Vanbiotic Colombia, Ecuador
Vancam Mexico
Vancobact Egypt
Vancobiotic Peru
Vancocare India
Vancocin Australia, Austria, Canada, Great Britain, Hungary, India, Ireland, Luxembourg, Netherlands, Poland, Saudi Arabia, Sweden, Switzerland, United Arab Emirates, United States of America
Vancocina Brazil, Italy
Vancofar Peru
Vancogen India
Vancoled India, United Arab Emirates
Vancolon Egypt, Saudi Arabia, United Arab Emirates
Vancomate India
Vancomax Argentina, Ecuador, Iran, Peru
Vancomicina Argentina, Chile, Colombia, Ecuador, Italy, Mexico, Portugal, Romania, Spain, Tunisia
Vancomix Egypt
Vancomycin Australia, Austria, Canada, Denmark, Egypt, Finland, Germany, Great Britain, Greece, Hungary, Iceland, Ireland, New Zealand, Norway, Saudi Arabia, Sweden, United Arab Emirates, United States of America
Vancomycine Belgium, Egypt, France, Luxembourg, Morocco, Netherlands, Switzerland
Vanconat India
Vanconor Peru
Vancorin India, Malaysia, Turkey
Vancosan Germany, Greece
Vancoser India
Vancotek Turkey
Vancotex Italy
Vancox Mexico
Vankomisin Turkey
Vanlid India, Malaysia, Venezuela
Varedet Argentina, Colombia, Ecuador, Peru
Yestafhal Mexico
Zengac Italy
Stability of mixtures   injection   Stability of mixtures : Vancomycin hydrochloride     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass NaCl 0,9% or Glucose 5% 5 mg/ml
injection   Vancomycin hydrochloride   
injection   Cefpirome sulfate 50 mg/ml
23°C
8 Hour
Light 280
Level of evidence B+
Glass Sodium chloride 0,9% 0,025 mg/ml
injection   Vancomycin hydrochloride   
injection   Heparin sodium 9,75 UI/ml
23°C
85 Day
Not specified 3958
Biological analysis
Glass Sodium chloride 0,9% 2 & 5 mg/ml
injection   Vancomycin hydrochloride   
injection   Heparin sodium 2500 UI/ml
injection   Sodium citrate 22 & 40 mg/ml
37°C
72 Hour
Protect from light 3327
Level of evidence D
Glass Sodium chloride 0,9% 0,025 mg/ml
injection   Vancomycin hydrochloride   
injection   Heparin sodium 100 UI/ml
4°C
63 Day
Protect from light 1414
Biological analysis
Glass Sodium chloride 0,9% 0,025 mg/ml
injection   Vancomycin hydrochloride   
injection   Heparin sodium 9,75 UI/ml
4°C
85 Day
Not specified 3958
Biological analysis
Glass Glucose 5% 4.9 mg/ml
injection   Vancomycin hydrochloride   
injection   Palonosetron hydrochloride 27 µg/ml
25°C
4 Hour
Not specified 2228
Level of evidence A+
Glass Ringer’s lactate solution 5 mg/ml
injection   Vancomycin hydrochloride   
injection   Cefpirome sulfate 50 mg/ml
23°C
8 Hour
Light 280
Level of evidence B+
Glass Sodium chloride 0,45% 5 mg/ml
injection   Vancomycin hydrochloride   
injection   Cefpirome sulfate 50 mg/ml
23°C
8 Hour
Light 280
Level of evidence B+
Glass None 5 mg/ml
injection   Vancomycin hydrochloride   
injection   Ofloxacin 2 mg/ml
25°C
48 Hour
Not specified 889
Level of evidence D
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Aztreonam 4 mg/ml
32°C
7 Day
Not specified 284
Level of evidence B+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Aztreonam 4 mg/ml
4°C
31 Day
Protect from light 284
Level of evidence B+
Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Sodium citrate 40 mg/ml
23°C
72 Hour
Light 3951
Level of evidence C
Polyvinyl chloride Sodium chloride 0,9% 3 mg/ml
injection   Vancomycin hydrochloride   
injection   Sodium citrate 40 mg/ml
23°C
72 Hour
Light 3951
Level of evidence C
Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Aztreonam 4 mg/ml
23°C
31 Day
Not specified 284
Level of evidence B+
Polyvinyl chloride Sodium chloride 0,9% 3 mg/ml
injection   Vancomycin hydrochloride   
injection   Sodium citrate 40 mg/ml
4°C
72 Hour
Not specified 3951
Level of evidence C
Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Sodium citrate 40 mg/ml
4°C
72 Hour
Not specified 3951
Level of evidence C
Polyvinyl chloride Glucose 5% 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Aztreonam 4 mg/ml
23°C
14 Day
Not specified 284
Level of evidence B+
Polyvinyl chloride Dianéal® PD2 4.25% glucose (Baxter) 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Ceftazidime 0,5 mg/ml
24°C
24 Hour
1416
Level of evidence D
Polyvinyl chloride Dianéal® PD2 4.25% glucose (Baxter) 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Ceftazidime 0,5 mg/ml
37°C
12 Hour
Light 1416
Level of evidence D
Polyvinyl chloride Dianéal® PD2 4.25% glucose (Baxter) 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Ceftazidime 0,5 mg/ml
4°C
24 Hour
Light 1416
Level of evidence D
Polyvinyl chloride Dianéal® PD2 1.5% glucose (Baxter) 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Ceftazidime 0,5 mg/ml
24°C
24 Hour
1416
Level of evidence D
Polyvinyl chloride Dianéal® PD2 1.5% glucose (Baxter) 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Ceftazidime 0,5 mg/ml
37°C
12 Hour
1416
Level of evidence D
Polyvinyl chloride Dianéal® PD2 1.5% glucose (Baxter) 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Ceftazidime 0,5 mg/ml
4°C
24 Hour
1416
Level of evidence D
Polyvinyl chloride Extraneal® (Baxter) 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Gentamicin sulfate 0,02 mg/ml
25°C
14 Day
Protect from light 3888
Level of evidence D
Polyvinyl chloride Extraneal® (Baxter) 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Gentamicin sulfate 0,02 mg/ml
37°C
4 Day
Protect from light 3888
Level of evidence D
Polypropylene Sodium chloride 0,9% 0,1 mg/ml
injection   Vancomycin hydrochloride   
injection   Heparin sodium 5000 UI/ml
4°C
28 Day
Not specified 3956
Biological analysis
Polypropylen Syringe Water for Injection 5 mg/ml
injection   Vancomycin hydrochloride   
injection   Paracetamol 10 mg/ml
25°C
4 Hour
Not specified 3571
Level of evidence A+
Polypropylen Syringe Sodium chloride 0,9% 0,025 mg/ml
injection   Vancomycin hydrochloride   
injection   Heparin sodium 100 UI/ml
4°C
14 Day
Protect from light 895
Biological analysis
Not specified Sodium chloride 0,9% 1 mg/ml
injection   Vancomycin hydrochloride   
injection   Sodium citrate 40 mg/ml
37°C
72 Hour
Light 3951
Level of evidence C
Not specified Sodium chloride 0,9% 3 mg/ml
injection   Vancomycin hydrochloride   
injection   Sodium citrate 40 mg/ml
37°C
72 Hour
Light 3951
Level of evidence C
Not specified Glucose 5% 0,5 mg/ml
injection   Vancomycin hydrochloride   
injection   Famotidine 0,2 mg/ml
25°C
14 Day
Protect from light 1748
Level of evidence B
Not specified Glucose 5% 0,5 mg/ml
injection   Vancomycin hydrochloride   
injection   Famotidine 0,2 mg/ml
4°C
14 Day
Protect from light 1748
Level of evidence B
  Mentions Légales