Last update :
29/10/2024
Curarimimetic   Atracurium besylate  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Abbocurium Poland
Acurmil Italy
Ancour Iran
Anecur Iran
Atacur Saudi Arabia
Atacurin Iran
Atrabesylate Egypt
Atracur Ecuador
Atracurio Argentina, Brazil, Spain
Atracurio besilato Chile, Italy, Peru, Venezuela
Atracurium Argentina, Austria, Egypt, Germany, Great Britain, Iran, Italy, Malaysia, Saudi Arabia, Sweden, United Arab Emirates
Atracurium besilat Austria
Atracurium besilate Australia, Canada, Egypt, Iran, New Zealand, Saudi Arabia, United Arab Emirates, United States of America
Atralex Malaysia
Atrasyl Turkey
Besilato Atracurio Chile, Portugal, Spain
Besitrac Brazil
Faulcurium Egypt, Portugal
Gelolagar Argentina
Laurak Spain
Neucurium Turkey
Notrixum Turkey
Relactrac Colombia
Relatrac Mexico
Tracrium Argentina, Australia, Austria, Belgium, Chile, Colombia, Ecuador, Egypt, France, Germany, Great Britain, Greece, Hungary, Iran, Italy, Luxembourg, Malaysia, Mexico, Morocco, Netherlands, New Zealand, Poland, Portugal, Romania, Saudi Arabia, Spain, Sweden, Switzerland, Tunisia, United Arab Emirates, United States of America
Tracumek Peru
Tracurix Argentina
Tracuron Argentina
References   injection   References : Atracurium besylate  
Type Publication
285 Journal Elmore RL, Contois ME, Kelly J, Noe A, Poirier A.
Stability and compatibility of admixtures of intravenous ciprofloxacin and selected drugs.
Clin Ther 1996 ; 18: 246-255.
300 Journal Trissel LA, Gilbert DL, Martinez JF.
Compatibility of propofol injectable emulsion with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 1287-1292.
319 Journal Hadzija BW, Lubarsky DA.
Compatibility of etomidate, thiopental sodium, and propofol injections with drugs commonly administered during induction of anesthesia.
Am J Health-Syst Pharm 1995 ; 52: 997-999.
402 Journal Savitsky ME.
Visual compatibility of neuromuscular blocking agents with various injectable drugs during simulated Y-site injection.
Am J Hosp Pharm 1990 ; 47: 820-821.
657 Journal Pramar YV, Loucas VA, Word D.
Chemical stability and adsorption of atracurium besylate injections in disposable plastic syringes.
J Clin Pharm Ther 1996 ; 21: 173-175.
660 Journal Michaels MR, Stauffer GL, Haas DP.
Propofol compatibility with other intravenous drug products - Two new methods of evaluating IV emulsion compatibility.
Ann Pharmacotherapy 1996 ; 30: 228-232.
813 Journal Akkermann SR, Zhang H, Mullins RE, Yaughn K.
Stability of milrinone lactate in the presence of 29 critical care drugs and 4 IV solutions.
Am J Health-Syst Pharm 1999 ; 56: 63-68.
865 Journal Bhatt-Mehta V, Hirata S.
Physical compatibility and chemical stability of atracurium besylate and midazolam hydrochloride during intravenous coinfusion.
Int J Pharm Compound 1998 ; 2: 79-81.
939 Journal Gilbar PJ, Groves CF.
Visual compatibility of total parenteral nutrition solution (Synthamin 17 Premix*) with selected drugs during simulated Y-site injection.
Aust J Hosp Pharm 1994 ; 24: 167-170.
1093 Journal Fisher DM, Canfell, Miller RD.
Stability of atracurium administered by infusion.
Anesthesiology 1984 ; 61: 347-348.
1611 Journal Chalmers JR, Bobek MB, Militello MA.
Visual compatibility of amiodarone hydrochloride injection with various intravenous drugs.
Am J Health-Syst Pharm 2001 ; 58: 504-506.
1647 Journal Ackland G.
Physical incompatibility between atracurium and intravenous diclofenac.
Anaesthesia 2001 ; 56: 294.
1721 Journal Trissel LA, Williams KY, Baker MB.
Compatibility screening of Hextend during simulated Y-site administration with other drugs.
Int J Pharm Compound 2001 ; 5: 69-72.
1803 Journal Trissel, LA, Saenz CA, Ogundele OB, Ingram D, Baker MB.
Compatibility of fenoldopam mesylate with other drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2003 ; 60: 80-85.
3373 Journal Khan S, Stannard N, Greijn J.
Precipitation of thiopental with muscle relaxants: a potential hazard.
J R Soc Med Sh Rep 2011 ; 2: 58.
3502 Manufacturer Propofol (Diprivan®) - Summary of Products Characteristics
Astra Zeneca 2012
3629 Manufacturer Atracurium (Atracurium solution for injection/infusion®) - Summary of Product Characteristics
Actavis UK 2014
3659 Manufacturer Propofol (Diprivan®) - Résumé des caractéristiques du produit
AstraZeneca 2016
3676 Manufacturer Atracurium bésilate (Atracurium Hospira®) - Résumé des caractéristiques du produit
Hospira 2014
4428 Journal Rashed S.M, Sweatman T.W, Thoma L, Hovinga C.A, Phelps S.J.
Chemical Compatibility of Depacon® with Medications Frequently Administered by Intravenous Y-Site Delivery in Patients with Epilepsy or Head Trauma.
J Pediatr Pharmacol Ther 2004 ; 9, 2: 126-132.

  Mentions Légales