Last update :
19/11/2024
Antibiotic   Imipenem-Cilastatin / Relebactam  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Recarbrio Finland, France, Great Britain, Italy, Norway, Sweden, United States of America
Compatibility   injection   Compatibility : Imipenem-Cilastatin / Relebactam              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Bumetanide 0,25 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Calcium chloride 40 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Calcium gluconate 40 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Cisatracurium besylate 0,4 mg/ml
NaCl 0,9% or Glucose 5% 4433
Modification of pH > 1 pH unit Incompatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Dexamethasone sodium phosphate 1 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Digoxin 0,25 µg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Diltiazem hydrochloride 5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Diphenhydramine hydrochloride 50 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Dobutamine hydrochloride 4 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Dopamine hydrochloride 3,2 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Enalaprilate 1,25 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Epinephrine hydrochloride 50 µg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Eptifibatide 2 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Esmolol hydrochloride 10 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Esomeprazole sodium 0,8 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Famotidine 4 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Fentanyl citrate 50 µg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Fosphenytoin sodium 37,5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Modification of pH > 1 pH unit Incompatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Furosemide 10 mg/ml
NaCl 0,9% or Glucose 5% 4433
Immediate turbidity Incompatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Haloperidol lactate 5 mg/ml
Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Heparin sodium 1000 UI/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Human albumin 50 mg/ml
NaCl 0,9% or Glucose 5% 4433
Modification of pH > 1 pH unit Incompatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Insulin 1 UI/ml
Sodium chloride 0,9% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Insulin aspart 1 UI/ml
Sodium chloride 0,9% 4433
Modification of pH > 1 pH unit Incompatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Insulin glulisine 1 U/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Insulin lyspro 1 UI/ml
Sodium chloride 0,9% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Ketorolac tromethamine 30 mg/ml
NaCl 0,9% or Glucose 5% 4433
Modification of pH > 1 pH unit Incompatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Labetalol hydrochloride 2 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Lidocaine hydrochloride 10 mg/ml
Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Magnesium sulfate 200 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Mesna 20 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Methylprednisolone sodium succinate 5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Metoclopramide hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Metoprolol tartrate 1 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Midazolam hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Milrinone lactate 0,2 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Naloxone hydrochloride 0,004 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Nitroglycerin 0,4 mg/ml
Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Norepinephrine bitartrate 0,032 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Pantoprazole sodium 4 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Phenylephrine hydrochloride 0,2 mg/ml
NaCl 0,9% or Glucose 5% 4433
Immediate turbidity Incompatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Phenytoin sodium 5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Potassium phosphate 0,4 mmol/ml
NaCl 0,9% or Glucose 5% 4433
Immediate turbidity Incompatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Propofol 10 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Ranitidine hydrochloride 2,5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Rocuronium bromide 5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Imipenem-Cilastatin / Relebactam 5/5/2,5 mg/ml
injection Sulbactam/durlobactam 15/15 mg/ml
Sodium chloride 0,9% 4801
Compatible
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
injection Vasopressin 1 UI/ml
NaCl 0,9% or Glucose 5% 4433

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