Monographie - Daratumumab - Stabilis 4.0

Last update :
19/11/2024

Anticancer drug

Daratumumab

injection

Stability in solutions

Stability of mixtures

Factors which affect stability

Compatibility

Route of administration

References

pdf

Tradename

Tradename

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Darzalex

Argentina, Austria, Belgium, Brazil, Chile, Denmark, France, Germany, Great Britain, Italy, Mexico, Netherlands, Norway, Peru, Spain, Sweden, Switzerland, United States of America

Stability in solutions

injection

Stability in solutions : Daratumumab

Container

Solvent

Concentration

Temperature

Storage

Duration of stability

References

Polyvinyl chloride

Sodium chloride 0,9%

0,8 >> 3,2 mg/mL

15-25°C

Light

15

Hour

Manufacturer's stability data

Polyvinyl chloride

Sodium chloride 0,9%

0,8 >> 3,2 mg/mL

2-8°C

Protect from light

24

Hour

Manufacturer's stability data

Polyethylene

Sodium chloride 0,9%

0,8 >> 3,2 mg/mL

15-25°C

Light

15

Hour

Manufacturer's stability data

Polyethylene

Sodium chloride 0,9%

0,8 >> 3,2 mg/mL

2-8°C

Protect from light

24

Hour

Manufacturer's stability data

Polypropylene

Sodium chloride 0,9%

0,8 >> 3,2 mg/mL

15-25°C

Light

15

Hour

Manufacturer's stability data

Polypropylene

Sodium chloride 0,9%

0,8 >> 3,2 mg/mL

2-8°C

Protect from light

24

Hour

Manufacturer's stability data

Polyolefine

Sodium chloride 0,9%

0,8 >> 3,2 mg/mL

15-25°C

Light

15

Hour

Manufacturer's stability data

Polyolefine

Sodium chloride 0,9%

0,8 >> 3,2 mg/mL

2-8°C

Protect from light

24

Hour

Manufacturer's stability data

Polypropylen Syringe

None

120 mg/mL

15-25°C

Not specified

24

Hour

Polypropylen Syringe

None

120 mg/mL

2-8°C

Protect from light

28

Day

Level of evidence C

Polypropylen Syringe

None

120 mg/mL

2-8°C

Not specified

24

Hour

Polypropylen Syringe

None

120 mg/mL

20-24°C

Protect from light

28

Day

Level of evidence C

Mentions Légales