Last update :
19/11/2024
References   References 66  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Avelar MA, Walker SE.
Title : Stability and compatibility of reconstituted hydromorphone with potassium chloride or heparin.
Reference : Can J Hosp Pharm ; 49: 140-145. 1996

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionHeparin sodium Anticoagulant
Incompatible <12,5 UI/ml + injectionHydromorphone hydrochloride >25 mg/ml + Water for Injection
Incompatible <1 UI/ml + injectionHydromorphone hydrochloride >10 mg/ml + Water for Injection
Compatible + injectionHydromorphone hydrochloride <12.5 mg/ml + Water for Injection
Incompatible <12,5 UI/ml + injectionHydromorphone hydrochloride >25 mg/ml + Sodium chloride 0,9%
Compatible + injectionHydromorphone hydrochloride <12.5 mg/ml + Sodium chloride 0,9%
injectionHydromorphone hydrochloride Analgesic
Incompatible >25 mg/ml + injectionHeparin sodium <12,5 UI/ml + Water for Injection
Incompatible >10 mg/ml + injectionHeparin sodium <1 UI/ml + Water for Injection
Compatible <12.5 mg/ml + injectionHeparin sodium + Water for Injection
Incompatible >25 mg/ml + injectionHeparin sodium <12,5 UI/ml + Sodium chloride 0,9%
Compatible <12.5 mg/ml + injectionHeparin sodium + Sodium chloride 0,9%
Compatible 25 mg/ml + injectionPotassium chloride 1000 mEq/l + Water for Injection
Compatible 5 >> 20 mg/ml + injectionPotassium chloride 500 & 1000 mEq/l + Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 1000 mEq/l + injectionHydromorphone hydrochloride 25 mg/ml + Water for Injection
Compatible 500 & 1000 mEq/l + injectionHydromorphone hydrochloride 5 >> 20 mg/ml + Glucose 5%

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