Last update :
19/11/2024
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References   References 4651  
Type : Journal
Web link : 10.1007/s00431-020-03854-7
Research teams :
Authors : De Basagoiti A, Katsumiti A, Abascal S, Bustinza A, López-Giménez L.R, Pascual P, De Miguel M, Campino A.
Title : Physical compatibility of alprostadil with selected drugs commonly used in the neonatal intensive care units.
Reference : Eur J Pedia ;180,1169–1176. 2021
Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
injectionAlprostadil Vasodilator
Compatible 20 µg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
Compatible 20 µg/ml + injectionCalcium gluconate 10 mg/ml + Glucose 5%
Incompatible 20 µg/ml + injectionCisatracurium besylate 1,2 mg/ml + Glucose 5%
Incompatible 20 µg/ml + injectionDexmedetomidine 4 µg/ml + Glucose 5%
Compatible 20 µg/ml + injectionDobutamine hydrochloride 10 mg/ml + Glucose 5%
Compatible 20 µg/ml + injectionDopamine hydrochloride 10 mg/ml + Glucose 5%
Compatible 20 µg/ml + injectionEpinephrine hydrochloride 200 µg/ml + Glucose 5%
Compatible 20 µg/ml + injectionFentanyl citrate 40 µg/ml + Glucose 5%
Compatible 20 µg/ml + injectionFlecainide acetate 2 mg/ml + Glucose 5%
Compatible 20 µg/ml + injectionFurosemide 5 mg/ml + Glucose 5%
Compatible 20 µg/ml + injectionHeparin sodium 1 UI/ml + Glucose 5%
Incompatible 20 µg/ml + injectionInsulin 1 UI/ml + Sodium chloride 0,9%
Compatible 20 µg/ml + injectionKetamine hydrochloride 5 mg/ml + Glucose 5%
Compatible 20 µg/ml + injectionMidazolam hydrochloride 2,5 mg/ml + Glucose 5%
Compatible 20 µg/ml + injectionMilrinone lactate 0,5 mg/ml + Glucose 5%
Compatible 20 µg/ml + injectionMorphine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 20 µg/ml + injectionNorepinephrine bitartrate 0,5 mg/ml + Glucose 5%
injectionAmiodarone hydrochloride Anti-arrhythmic
Compatible 6 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionCalcium gluconate Electrolyte
Compatible 10 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionCisatracurium besylate Curarimimetic
Incompatible 1,2 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionDexmedetomidine Sympathomimetic
Incompatible 4 µg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 10 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 10 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 200 µg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionFentanyl citrate Analgesic
Compatible 40 µg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionFlecainide acetate Anti-arrhythmic
Compatible 2 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionFurosemide Diuretic
Compatible 5 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Compatible 1 UI/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionInsulin Glucose-lowering
Incompatible 1 UI/ml + injectionAlprostadil 20 µg/ml + Sodium chloride 0,9%
injectionKetamine hydrochloride General anesthetic
Compatible 5 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Compatible 2,5 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionMilrinone lactate Cardiotonic
Compatible 0,5 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionMorphine hydrochloride Analgesic
Compatible 2 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
injectionNorepinephrine bitartrate Sympathomimetic
Incompatible 0,5 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
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