Last update :
03/05/2024
References   References 3989  
Type : Journal
Web link : https://www.degruyter.com/view/j/pthp.2017.2.issue-1/pthp-2017-0013/pthp-2017-0013.xml?format=INT

Research teams : Lille - Faculté des Sciences Pharmaceutiques et Biologiques
Authors : Feutry F, Genay S, Velghe C, Barthélémy C, Décaudin B, Odou, P.
Title : Stability of midazolam and noradrenaline stored in cyclic olefin copolymer AT-Closed Vials® and polypropylene syringes during 365 days.
Reference : Pharmaceutical Technology in Hospital Pharmacy ; 2,1: 35 2017

Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
The method is not specified (poster, letter to the editor)

List of drugs
InjectionMidazolam hydrochloride Anxiolytic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml -20°C Protect from light
365 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml 5°C Protect from light
365 Day
Stability in solutions AT-Closed vial® Sodium chloride 0,9% 1 mg/ml -20°C Protect from light
365 Day
Stability in solutions AT-Closed vial® Sodium chloride 0,9% 1 mg/ml 5°C Protect from light
365 Day
InjectionNorepinephrine bitartrate Sympathomimetic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0.2 mg/ml -20°C Protect from light
365 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0.2 mg/ml 5°C Protect from light
365 Day
Stability in solutions AT-Closed vial® Sodium chloride 0,9% 0.2 mg/ml -20°C Protect from light
365 Day
Stability in solutions AT-Closed vial® Sodium chloride 0,9% 0.2 mg/ml 5°C Protect from light
365 Day

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