Bibliographie - 3981 - Stabilis 4.0

Senaste uppdateringen :
18/07/2024

Hänvisningar 3981

Typ :

tidningen

internet länkar :

http://dx.doi.org/10.1136/ejhpharm-2016-000980

forskargrupper :

Wuhan - Wuhan University, College of Pharmacy

Författare :

He G, Zeng F, Lei K, Xia S, Deng L, Zhang C, Liu D.

Titel :

Compatibility of dexamethasone sodium phosphate with 5-HT3 receptor antagonists in infusion solutions: a comprehensive study

Hänvisningar :

EJHP ;24:162?166 2017

Evidensgrad :

fysikalisk stabilitet :

kemisk stabilitet :

High Performance Liquid Chromatography - ultraviolet detector (HPLC-UVD)

Stabilitet definieras som 95% av den initiala koncentrationen

andra metoder :

Kommentarer :

Nedbrytningsprodukter som inte observerats under verkliga förhållanden

Förteckning över substanser

Azasetron

0.2 mg/ml

Dexamethasone sodium phosphate

0.1 & 0.2 mg/ml

Dexamethasone sodium phosphate

0.1 & 0.2 mg/ml	+ Azasetron	0.2 mg/ml	+
0.1 & 0.2 mg/ml	+ Dolasetron mesylate	0.05 mg/ml	+
0.1 & 0.2 mg/ml	+ Dolasetron mesylate	1 mg/ml	+
0.1 & 0.2 mg/ml	+ Ondansetron hydrochloride	0.08 mg/ml	+
0.1 & 0.2 mg/ml	+ Palonosetron hydrochloride	2.5 µg/ml	+
0.1 & 0.2 mg/ml	+ Ramosetron	3 µg/ml	+

Dolasetron mesylate

	0.05 mg/ml	+ Dexamethasone sodium phosphate	0.1 & 0.2 mg/ml	+
	1 mg/ml	+ Dexamethasone sodium phosphate	0.1 & 0.2 mg/ml	+

Ondansetron hydrochloride

0.08 mg/ml

Dexamethasone sodium phosphate

0.1 & 0.2 mg/ml

Palonosetron hydrochloride

2.5 µg/ml

Dexamethasone sodium phosphate

0.1 & 0.2 mg/ml

Ramosetron

3 µg/ml

Dexamethasone sodium phosphate

0.1 & 0.2 mg/ml

Tropisetron hydrochloride

23-27°C

Dexamethasone sodium phosphate	0,1 mg/ml
Ondansetron hydrochloride	0,08 mg/ml

23-27°C

Dexamethasone sodium phosphate	0,2 mg/ml
Ondansetron hydrochloride	0,08 mg/ml

23-27°C

Dexamethasone sodium phosphate	0,2 mg/ml
Palonosetron hydrochloride	2.5 µg/ml

23-27°C

Dexamethasone sodium phosphate	0,1 mg/ml
Palonosetron hydrochloride	2.5 µg/ml

23-27°C

Ramosetron	3 µg/ml
Dexamethasone sodium phosphate	0,1 mg/ml

23-27°C

Dexamethasone sodium phosphate	0.2 mg/ml
Ramosetron	3 µg/ml

23-27°C

Dexamethasone sodium phosphate	0,2 mg/ml
Tropisetron hydrochloride	0,05 mg/ml

23-27°C

Tropisetron hydrochloride	0,05 mg/ml
Dexamethasone sodium phosphate	0,1 mg/ml

23-27°C

Dexamethasone sodium phosphate	0,1 mg/ml
Dolasetron mesylate	1 mg/ml

23-27°C

Dexamethasone sodium phosphate	0,2 mg/ml
Dolasetron mesylate	1 mg/ml

23-27°C

Azasetron	0,2 mg/ml
Dexamethasone sodium phosphate	0,1 mg/ml

23-27°C

Dexamethasone sodium phosphate	0,2 mg/ml
Azasetron	0,2 mg/ml

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