Last update :
03/05/2024
References   References 39  
Type : Journal
Web link : http://www.john-libbey-eurotext.fr/fr/revues/bio_rech/jpc/e-docs/00/02/71/4F/article.md?type=text.html

Research teams : Créteil - Hôpital intercommunal de Créteil,
Authors : Farhang-Asnafi S, Callaert S, Barre J, Tillement JP, Thebault A.
Title : Influence of intravenous admixtures on the stability of the new solution of 5-fluorouracil.
Reference : J Pharm Clin ; 16: 45-48. 1997

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
No comments for the degradation products

List of drugs
InjectionFluorouracil Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 5 mg/ml 25°C Light
13 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 5 mg/ml 4°C Protect from light
13 Day

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