Last update :
28/04/2024
References   References 389  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, DeAngelis C, Iazzetta J, Eppel JG.
Title : Compatibility of dexamethasone sodium phosphate with hydromorphone hydrochloride or diphenhydramine hydrochloride.
Reference : Am J Hosp Pharm ; 48: 2161-2166. 1991

Level of Evidence : 
Physical stability : 
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List of drugs
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 >> 10 mg/ml + InjectionDiphenhydramine hydrochloride < 5 mg/ml
Compatible 2 mg/ml + InjectionDiphenhydramine hydrochloride 40 mg/ml
Incompatible 2 >> 10 mg/ml + InjectionDiphenhydramine hydrochloride 5 >> 35 mg/ml
Incompatible > 3 mg/ml + InjectionHydromorphone hydrochloride > 15 mg/ml
Compatible < 2 mg/ml + InjectionHydromorphone hydrochloride 1 >> 40 mg/ml
Compatible 2 >> 10 mg/ml + InjectionHydromorphone hydrochloride < 10 mg/ml
InjectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible < 5 mg/ml + InjectionDexamethasone sodium phosphate 4 >> 10 mg/ml
Compatible 40 mg/ml + InjectionDexamethasone sodium phosphate 2 mg/ml
Incompatible 5 >> 35 mg/ml + InjectionDexamethasone sodium phosphate 2 >> 10 mg/ml
InjectionHydromorphone hydrochloride Analgesic
Incompatible > 15 mg/ml + InjectionDexamethasone sodium phosphate > 3 mg/ml
Compatible 1 >> 40 mg/ml + InjectionDexamethasone sodium phosphate < 2 mg/ml
Compatible < 10 mg/ml + InjectionDexamethasone sodium phosphate 2 >> 10 mg/ml

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