Last update :
19/11/2024
References   References 3075  
Type : Journal

Research teams : Clermont-Ferrand - University Hospital Gabriel Monpied, Department of Pharmacy
Authors : Balayssac D, Badaroux L, Rodier C, Sautou-Miranda V, Bazin JE, Chopineau J.
Title : Compatibility and stability of parenteral analgesic admixtures for multimodal analgesia
Reference : EJHP Science ; 15, 4: 78-82. 2009

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionKetoprofene Anti-inflammatory
Stability in solutions Glass Sodium chloride 0,9% 0,96 mg/ml 20-24°C Light
24 Hour
injectionNefopam Analgesic
Stability in solutions Glass Sodium chloride 0,9% 0,19 mg/ml 20-24°C Light
24 Hour
injectionParacetamol Analgesic
injectionTramadol hydrochloride Analgesic
Stability in solutions Glass Sodium chloride 0,9% 0,89 mg/ml 20-24°C Light
24 Hour
Stability of mixtures
Glass Sodium chloride 0,9% 20-24°C Light
injection Ketoprofene 0,95 mg/ml
injection Tramadol hydrochloride 0,97 mg/ml
24 Hour
Glass Sodium chloride 0,9% 20-24°C Light
injection Ketoprofene 0,93 mg/ml
injection Nefopam 0,21 mg/ml
24 Hour
Glass None 20-24°C Light
injection Paracetamol 10 mg/ml
injection Nefopam 0,2 mg/ml
24 Hour
Glass None 20-24°C Light
injection Paracetamol 10,63 mg/ml
injection Ketoprofene 1 mg/ml
24 Hour
Glass None 20-24°C Light
injection Paracetamol 9,44 mg/ml
injection Tramadol hydrochloride 0,94 mg/ml
24 Hour
Glass None 20-24°C Light
injection Paracetamol 9,86 mg/ml
injection Ketoprofene 0,96 mg/ml
injection Nefopam 0,20 mg/ml
24 Hour
Glass None 20-24°C Light
injection Paracetamol 10,04 mg/ml
injection Ketoprofene 0,96 mg/ml
injection Tramadol hydrochloride 0,96 mg/ml
24 Hour

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