| tüüp : |
ajaleht |
| interneti link : |
https://ijpc.com/Abstracts/Abstract.cfm?ABS=857 |
|
| uurimisrühmad : |
Tolède - College of Pharmacy and Pharmaceutical Sciences, The University of Toledo |
| Autor : |
Alexander KS, Sundar S, White DB, Dollimore D. |
| pealkiri : |
The Formulation Development and Stability of Spironolactone Suspension |
| publikatsioon : |
Int J Pharm Compound ; 1, 3: 195-199. 1997 |
|
| Tõendite tase : |
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| füüsikaline stabiilsus : |
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| Keemiline püsivus : |
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| Muud meetodid : |
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| Kommentaarid : |
|
ingredientide nimekiri
 Spironolactone
|
 |
 |
pH |
pH 4.5 |
 |
 |
 |
 |
 |
600 mg
®= ? |
| Karboksümetüültselluloos |
900 mg |
| Veegum® |
900 mg |
| Metüülparabeen |
120 mg |
| propüülparabeen |
24 mg |
| propüleenglükool |
1.2 ml |
| sorbitool |
70% 48 ml |
| Naatriumatsetaat |
350 mg |
| Äädikhape |
36% 0.67 ml |
| naatriumbisulfit |
120 mg |
| dinaatriumedetaat |
120 mg |
| naatriumsahhariin |
24 mg |
| Ananassi aroom |
|
| destilleeritud vesi |
>> 120 ml |
|
30°C |
 |
| 90 |
 |
|
|
|
|
|
600 mg
®= ? |
| Karboksümetüültselluloos |
900 mg |
| Veegum® |
900 mg |
| Metüülparabeen |
120 mg |
| propüülparabeen |
24 mg |
| propüleenglükool |
1.2 ml |
| sorbitool |
70% 48 ml |
| Naatriumatsetaat |
350 mg |
| Äädikhape |
36% 0.67 ml |
| naatriumbisulfit |
120 mg |
| dinaatriumedetaat |
120 mg |
| naatriumsahhariin |
24 mg |
| Ananassi aroom |
|
| destilleeritud vesi |
>> 120 ml |
|
5°C |
|
| 90 |
|
|
|
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|
