Type : |
Journal |
|
forskerhold : |
Tolède - College of Pharmacy and Pharmaceutical Sciences, The University of Toledo |
Forfattere : |
Alexander KS, Sundar S, White DB, Dollimore D. |
Titel : |
The Formulation Development and Stability of Spironolactone Suspension |
Nummer : |
Int J Pharm Compound ; 1, 3: 195-199. 1997 |
|
cotationvaleur : |
|
fysisk stabilitet : |
|
kemisk stabilitet : |
|
andre metoder : |
|
Kommentarer : |
|
Lister
Spironolactone
|
|
|
pH |
pH 4.5 |
|
|
|
|
|
600 mg ®= ? |
Carboxymethylcellulose |
900 mg |
Veegum® |
900 mg |
Methylparaben |
120 mg |
Propylparaben |
24 mg |
Propylenglycol |
1.2 ml |
Sorbitol |
70% 48 ml |
Natriumacetat |
350 mg |
Eddikesyre |
36% 0.67 ml |
Natriumbisulfit |
120 mg |
Natriumedetat |
120 mg |
Natriumsaccharin |
24 mg |
Ananasaroma |
|
Destilleret vand |
>> 120 ml |
|
30°C |
|
90 |
|
|
|
|
|
|
600 mg ®= ? |
Carboxymethylcellulose |
900 mg |
Veegum® |
900 mg |
Methylparaben |
120 mg |
Propylparaben |
24 mg |
Propylenglycol |
1.2 ml |
Sorbitol |
70% 48 ml |
Natriumacetat |
350 mg |
Eddikesyre |
36% 0.67 ml |
Natriumbisulfit |
120 mg |
Natriumedetat |
120 mg |
Natriumsaccharin |
24 mg |
Ananasaroma |
|
Destilleret vand |
>> 120 ml |
|
5°C |
|
90 |
|
|
|
|
|