| Type : |
Journal |
| Web link : |
https://doi.org/10.1046/j.0269-4727.2003.00515.x |
|
| Research teams : |
Singapore - Department of Pharmacy, Faculty of Science, National University of Singapore |
| Authors : |
Tan LK, Thenmozhiyal JC, Ho PC. |
| Title : |
Stability of extemporaneously prepared saquinavir formulations |
| Reference : |
J Clin Pharm Ther ; 28: 457-463. 2003 |
|
| Level of Evidence : |
|
| Physical stability : |
|
| Chemical stability : |
|
| Other methods : |
|
| Comments : |
|
List of drugs
Saquinavir
|
 |
 |
pH |
pH = 4 |
 |
 |
 |
 |
 |
200 mg Fortovase® |
| Ethanol |
4 mL |
| Citric acid |
100 mg |
| Simple syrup |
2 mL |
| Purified water |
>> 20 mL |
| pH= |
4 |
|
25°C |
 |
| 30 |
 |
|
|
 |
 |
 |
200 mg Fortovase® |
| Ethanol |
4 mL |
| Citric acid |
100 mg |
| Simple syrup |
2 mL |
| Purified water |
>> 20 mL |
| pH= |
4 |
|
5°C |
 |
| 30 |
 |
|
|
|
|