Last update :
19/11/2024
References   References 2522  
Type : Journal

Research teams : Columbus - The Ohio State University Hospitals, Department of Pharmacy
Authors : Nahata MC, Morosco RS, Hipple TF.
Title : Stability of captopril in liquid containing ascorbic acid or sodium ascorbate
Reference : Am J Hosp Pharm ; 51: 1707-1708. 1994

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Oral solutionCaptopril Antihypertensive
Factors which affect stability Temperature Increase Induces Degradation
Stability in solutions Glass tablets 100 mg
®=? (Squibb&sons)
Sodium ascorbate 500mg
Purified water qsp100ml
21-23°C Not specified
14 Day
Stability in solutions Glass tablets 100 mg
®=? (Squibb&sons)
Ascorbic acid 500mg
Purified water qsp100ml
21-23°C Not specified
28 Day
Stability in solutions Glass tablets 100 mg
®=? (Squibb&Sons)
Sodium ascorbate 500 mg
Distilled water >> 100 ml
4°C Not specified
56 Day
Stability in solutions Glass tablets 100 mg
®=? (Squibb&Sons)
Ascorbic acid 500 mg
Distilled water >> 100 ml
4°C Not specified
56 Day

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