Last update :
19/11/2024
References   References 240  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/52/17/1904

Research teams : San Francisco - Genentech, Inc
Authors : Lam XM, Ward CA, de C du M?e CPR.
Title : Stability and activity of alteplase with injectable drugs commonly used in cardiac therapy.
Reference : Am J Health-Syst Pharm ; 52: 1904-1909. 1995

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAlteplase Thrombolytic
Incompatible 0.5 mg/ml + injectionDobutamine hydrochloride 5 mg/ml + Water for Injection
Incompatible 0.5 mg/ml + injectionDopamine hydrochloride 0.8 mg/ml + Water for Injection
Incompatible 0.5 mg/ml + injectionHeparin sodium 40 UI/ml + Water for Injection
Compatible 0.5 mg/ml + injectionLidocaine hydrochloride 4 mg/ml + Water for Injection
Compatible 0.5 mg/ml + injectionMetoprolol tartrate 0.5 mg/ml + Water for Injection
Incompatible 0.5 mg/ml + injectionMorphine sulfate 1 mg/ml + Water for Injection
Compatible 0.5 mg/ml + injectionNitroglycerin 0.4 mg/ml + Water for Injection
Compatible 0.5 mg/ml + injectionPropranolol hydrochloride 0.5 mg/ml + Water for Injection
injectionDobutamine hydrochloride Cardiotonic
Incompatible 5 mg/ml + injectionAlteplase 0.5 mg/ml + Water for Injection
injectionDopamine hydrochloride Cardiotonic
Incompatible 0.8 mg/ml + injectionAlteplase 0.5 mg/ml + Water for Injection
injectionHeparin sodium Anticoagulant
Incompatible 40 UI/ml + injectionAlteplase 0.5 mg/ml + Water for Injection
injectionLidocaine hydrochloride Local anesthetic
Compatible 4 mg/ml + injectionAlteplase 0.5 mg/ml + Water for Injection
injectionMetoprolol tartrate Anti-arrhythmic
Compatible 0.5 mg/ml + injectionAlteplase 0.5 mg/ml + Water for Injection
injectionMorphine sulfate Analgesic
Incompatible 1 mg/ml + injectionAlteplase 0.5 mg/ml + Water for Injection
injectionNitroglycerin Vasodilator
Compatible 0.4 mg/ml + injectionAlteplase 0.5 mg/ml + Water for Injection
injectionPropranolol hydrochloride Beta-blocker
Compatible 0.5 mg/ml + injectionAlteplase 0.5 mg/ml + Water for Injection

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