Last update :
06/05/2024
References   References 2305  
Type : Journal

Research teams : Le Locle - Codman Neuro Sciences SA RL
Authors : Bianchi F, Ginggen A, Tardy Y.
Title : Stability and compatibility of drug mixtures in an implantable infusion system.
Reference : Anaesthesia 63, 9: 972-978. 2008

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionBupivacaine hydrochloride Local anesthetic
Stability in solutions Glass Not specified 24 mg/ml 37°C Protect from light
90 Day
InjectionClonidine hydrochloride Antihypertensive
Stability in solutions Glass Not specified 2 mg/ml 37°C Protect from light
90 Day
InjectionHydromorphone hydrochloride Analgesic
Stability in solutions Glass Not specified 50 mg/ml 37°C Protect from light
90 Day
InjectionMorphine sulfate Analgesic
Stability in solutions Glass Not specified 50 mg/ml 37°C Protect from light
90 Day
Stability of mixtures
Not specified Sodium chloride 0,9% 37°C Protect from light
Injection Morphine sulfate 50 mg/ml
Injection Bupivacaine hydrochloride 24 mg/ml
Injection Clonidine hydrochloride 2 mg/ml
90 Day
Not specified Sodium chloride 0,9% 37°C Protect from light
Injection Hydromorphone hydrochloride 50 mg/ml
Injection Bupivacaine hydrochloride 24 mg/ml
Injection Clonidine hydrochloride 2 mg/ml
90 Day

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