Last update :
18/07/2024
References   References 2305  
Type : Journal

Research teams : Le Locle - Codman Neuro Sciences SA RL
Authors : Bianchi F, Ginggen A, Tardy Y.
Title : Stability and compatibility of drug mixtures in an implantable infusion system.
Reference : Anaesthesia 63, 9: 972-978. 2008

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionBupivacaine hydrochloride Local anesthetic
Stability in solutions Glass Not specified 24 mg/ml 37°C Protect from light
90 Day
injectionClonidine hydrochloride Antihypertensive
Stability in solutions Glass Not specified 2 mg/ml 37°C Protect from light
90 Day
injectionHydromorphone hydrochloride Analgesic
Stability in solutions Glass Not specified 50 mg/ml 37°C Protect from light
90 Day
injectionMorphine sulfate Analgesic
Stability in solutions Glass Not specified 50 mg/ml 37°C Protect from light
90 Day
Stability of mixtures
Not specified Sodium chloride 0,9% 37°C Protect from light
injection Morphine sulfate 50 mg/ml
injection Bupivacaine hydrochloride 24 mg/ml
injection Clonidine hydrochloride 2 mg/ml
90 Day
Not specified Sodium chloride 0,9% 37°C Protect from light
injection Hydromorphone hydrochloride 50 mg/ml
injection Bupivacaine hydrochloride 24 mg/ml
injection Clonidine hydrochloride 2 mg/ml
90 Day

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