Last update :
19/11/2024
References   References 225  
Type : Journal

Research teams : Ann Arbor - University of Michigan, College of Pharmacy
Authors : Bhatt-Mehta V, Johnson CE, Leininger N, Agarwal M.
Title : Stability of fentanyl citrate and midazolam hydrochloride during simulated intravenous coadministration.
Reference : Am J Health-Syst Pharm ; 52: 511-513. 1995

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed

List of drugs
injectionFentanyl citrate Analgesic
Compatible 20 & 40 µg/ml + injectionMidazolam hydrochloride 0.1 & 0.5 mg/ml + Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Compatible 0.1 & 0.5 mg/ml + injectionFentanyl citrate 20 & 40 µg/ml + Glucose 5%
Stability of mixtures
Glass Glucose 5% 23°C-25°C Light
injection Fentanyl citrate 20 & 40 µg/ml
injection Midazolam hydrochloride 0,1 & 0,5 mg/ml
3 Hour

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