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References   References 2114  
Type : Journal
Web link : https://doi.org/10.1345/aph.1G715
Research teams : Houston - M.D.Anderson Cancer Center
Authors : Zhang Y, Trissel LA.
Title : Physical and chemical stability of pemetrexed in infusion solutions.
Reference : Ann Pharmacotherapy ; 40, 6: 1082-1085. 2006
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
No comments for the degradation products
List of drugs
injectionPemetrexed disodium Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 2&10&20 mg/ml 23°C With or without light
24 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 2&10&20 mg/ml 4°C Protect from light
24 Hour
Compatible + Glucose 5%
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