Last update :
22/08/2024
References   References 2002  
Type : Journal

Research teams : Riyad - College of Pharmacy, King Saud University
Authors : Abanmy NO, Zaghloul IY, Radwan MA.
Title : Compatibility of tramadol hydrochloride injection with selected drugs and solutions.
Reference : Am J Health-Syst Pharm ; 62: 1299-1302. 2005

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAciclovir sodium Antiviral
Incompatible 5 mg/ml + injectionTramadol hydrochloride 0,4 mg/ml + Sodium chloride 0,9%
injectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 10/20 mg/ml + injectionTramadol hydrochloride 0,4 mg/ml + Sodium chloride 0,9%
injectionClindamycin phosphate Antibiotic
Incompatible 6 mg/ml + injectionTramadol hydrochloride 0,4 mg/ml + Sodium chloride 0,9%
injectionMannitol Various
Compatible 20 mg/ml + injectionTramadol hydrochloride 0,4 mg/ml + None
injectionOndansetron hydrochloride Antiemetic
Compatible 0,016 mg/ml + injectionTramadol hydrochloride 0,4 mg/ml + Sodium chloride 0,9%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 0,5 mg/ml + injectionTramadol hydrochloride 0,4 mg/ml + Sodium chloride 0,9%
injectionTramadol hydrochloride Analgesic
Incompatible 0,4 mg/ml + injectionAciclovir sodium 5 mg/ml + Sodium chloride 0,9%
Compatible 0,4 mg/ml + injectionAmpicillin sodium - sulbactam sodium 10/20 mg/ml + Sodium chloride 0,9%
Incompatible 0,4 mg/ml + injectionClindamycin phosphate 6 mg/ml + Sodium chloride 0,9%
Compatible 0,4 mg/ml + injectionMannitol 20 mg/ml + None
Compatible 0,4 mg/ml + injectionOndansetron hydrochloride 0,016 mg/ml + Sodium chloride 0,9%
Compatible 0,4 mg/ml + injectionRanitidine hydrochloride 0,5 mg/ml + Sodium chloride 0,9%

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