Bibliographie - 1955 - Stabilis 4.0

Last update :
27/11/2025

References 1955

Type :

Journal

Web link :

Research teams :

Houston - M.D.Anderson Cancer Center

Authors :

Trissel LA, Zhang Y.

Title :

Palonosetron HCl compatibility and stability with doxorubicin HCl and epirubicin HCl during simulated Y-site administration.

Reference :

Ann Pharmacotherapy ; 39: 280-283. 2005

Level of Evidence :

Physical stability :

Chemical stability :

Other methods :

Comments :

Degradation products not observed in real conditions

List of drugs

1 mg/ml

50 µg/ml

0,5 mg/ml

50 µg/ml

	50 µg/ml	+ Doxorubicin hydrochloride	1 mg/ml	+
	50 µg/ml	+ Epirubicin hydrochloride	0,5 mg/ml	+

23°C

Palonosetron hydrochloride	25 µg/ml
Doxorubicin hydrochloride	0,1 mg/ml

23°C

Palonosetron hydrochloride	26 µg/ml
Epirubicin hydrochloride	0,26 mg/ml

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