Last update :
19/11/2024
References   References 1665  
Type : Journal

Research teams : Westborough - AstraZeneca LP
Authors : Öster Svedberg K, McKenzie J, Larrivee-Elkins C.
Title : Compatibility of ropivacaine with morphine, sufentanil, fentanyl, or clonidine.
Reference : J Clin Pharm Ther ; 21: 39-45. 2002

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionClonidine hydrochloride Antihypertensive
Compatible 0.005 & 0.05 mg/ml + injectionRopivacain hydrochloride 1 & 2 mg/ml + Sodium chloride 0,9%
injectionFentanyl citrate Analgesic
Compatible 1 & 10 µg/ml + injectionRopivacain hydrochloride 1 & 2 mg/ml + Sodium chloride 0,9%
injectionMorphine sulfate Analgesic
Compatible 0.02 & 0.1 mg/ml + injectionRopivacain hydrochloride 1 & 2 mg/ml + Sodium chloride 0,9%
injectionRopivacain hydrochloride Local anesthetic
Compatible 1 & 2 mg/ml + injectionClonidine hydrochloride 0.005 & 0.05 mg/ml + Sodium chloride 0,9%
Compatible 1 & 2 mg/ml + injectionFentanyl citrate 1 & 10 µg/ml + Sodium chloride 0,9%
Compatible 1 & 2 mg/ml + injectionMorphine sulfate 0.02 & 0.1 mg/ml + Sodium chloride 0,9%
Compatible 1 & 2 mg/ml + injectionSufentanil citrate 0.0004 & 0.004 mg/ml + Sodium chloride 0,9%
injectionSufentanil citrate Analgesic
Compatible 0.0004 & 0.004 mg/ml + injectionRopivacain hydrochloride 1 & 2 mg/ml + Sodium chloride 0,9%
Stability of mixtures
Polypropylene Sodium chloride 0,9% 30°C Protect from light
injection Ropivacain hydrochloride 1 & 2 mg/ml
injection Morphine sulfate 0,02 mg/ml
30 Day
Polypropylene Sodium chloride 0,9% 30°C Protect from light
injection Ropivacain hydrochloride 1 & 2 mg/ml
injection Sufentanil citrate 0,0004 mg/ml
30 Day
Polypropylene Sodium chloride 0,9% 30°C Protect from light
injection Ropivacain hydrochloride 1 & 2 mg/ml
injection Fentanyl citrate 1 µg/ml
30 Day
Polypropylene Sodium chloride 0,9% 30°C Protect from light
injection Clonidine hydrochloride 0.05 & 0.005 mg/ml
injection Ropivacain hydrochloride 1 & 2 mg/ml
30 Day
Polypropylene Sodium chloride 0,9% 30°C Protect from light
injection Ropivacain hydrochloride 2 mg/ml
injection Morphine sulfate 0,1 mg/ml
30 Day
Polypropylene Sodium chloride 0,9% 30°C Protect from light
injection Sufentanil citrate 0,004 mg/ml
injection Ropivacain hydrochloride 2 mg/ml
30 Day
Polypropylene Sodium chloride 0,9% 30°C Protect from light
injection Ropivacain hydrochloride 2 mg/ml
injection Fentanyl citrate 10 µg/ml
30 Day
Polypropylene Sodium chloride 0,9% 30°C Protect from light
injection Clonidine hydrochloride 0.005 mg/ml
injection Ropivacain hydrochloride 2 mg/ml
30 Day

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