Last update :
18/04/2024
References   References 1614  
Type : Journal
Web link : http://www.factsandcomparisons.com/HospitalPharm/?id=30

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Xu QA, Zhang Y, Saenz CA, Ingram DS.
Title : Stability of ciprofloxacin and vancomycin hydrochloride in autodose infusion system bags.
Reference : Hosp Pharm ; 36: 1170-1173. 2001

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
Comments : 
No comments for the degradation products

List of drugs
InjectionCiprofloxacin lactate Antibiotic
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 4 mg/ml 23°C Protect from light
7 Day
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 4 mg/ml 4°C Protect from light
30 Day
InjectionVancomycin hydrochloride Antibiotic
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 10 mg/ml 23°C Protect from light
7 Day
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 10 mg/ml 4°C Protect from light
30 Day

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