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References   References 1405  
Type : Journal
Web link : https://doi.org/10.1046/j.1365-2710.1998.00141.x
Research teams : Hobart - University of Tasmania, School of Pharmacy
Authors : Peterson GM, Miller KA, Galloway JG, Dunne PF.
Title : Compatibility and stability of fentanyl admixtures in polypropylene syringes.
Reference : J Clin Pharm Ther ; 23: 67-72. 1998
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement Water loss by evaporation 
Comments : 
List of drugs
injectionFentanyl citrate Analgesic
injectionMetoclopramide hydrochloride Antiemetic
injectionMidazolam hydrochloride Anxiolytic
injectionScopolamine N-butyl bromide Antimuscarinic
Stability of mixtures
Polypropylen Syringe Water for Injection 32°C Protect from light
injection Fentanyl citrate 40 µg/ml
injection Scopolamine N-butyl bromide 0,85 mg/ml
injection Midazolam hydrochloride 0,6 mg/ml
10 Day
Polypropylen Syringe Water for Injection 32°C Protect from light
injection Midazolam hydrochloride 0,6 mg/ml
injection Metoclopramide hydrochloride 0,7 mg/ml
injection Fentanyl citrate 40 µg/ml
10 Day
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