Last update :
19/11/2024
References   References 1288  
Type : Journal

Research teams : Derby - Institute of Health and Community studies, Derbyshire college of higher education
Authors : Allwood MC, Brown PW, Lee M.
Title : Stability of injections containing diamorphine and midazolam in plastic syringes.
Reference : Int J Pharm Pract ; 3: 57-59. 1994

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
injectionDiamorphine hydrochloride Analgesic
Compatible 0,66 & 33 mg/ml + injectionMidazolam hydrochloride 0,66 & 5 mg/ml + Water for Injection
injectionMidazolam hydrochloride Anxiolytic
Compatible 0,66 & 5 mg/ml + injectionDiamorphine hydrochloride 0,66 & 33 mg/ml + Water for Injection
Stability of mixtures
Polypropylen Syringe Water for Injection 22°C Protect from light
injection Diamorphine hydrochloride 0,66 & 33 mg/ml
injection Midazolam hydrochloride 0,66 & 5 mg/ml
14 Day

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