Last update :
19/11/2024
References   References 120  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, Coons C, Matte D, DeAngelis C, Iazzetta J, Kolos C, Birkhans B.
Title : Hydromorphone and morphine stability in portable infusion pump cassettes and minibags.
Reference : Can J Hosp Pharm ; 41: 177-182. 1988

Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
No visual inspection

List of drugs
injectionHydromorphone hydrochloride Analgesic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 & 5 mg/ml 23°C Not specified
42 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 & 5 mg/ml 4°C Protect from light
42 Day
injectionMorphine sulfate Analgesic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 mg/ml 23°C Not specified
30 Day
Stability in solutions Polyvinyl chloride None 10 mg/ml 23°C Light
30 Day

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