Last update :
19/11/2024
References   References 117  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Vecchio M, Walker SE, Iazzetta J, Hardy BG.
Title : The stability of morphine intravenous infusion solutions.
Reference : Can J Hosp Pharm ; 41: 5-9. 1988

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Electrochemical detector
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
injectionMorphine sulfate Analgesic
Stability in solutions Glass NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 23°C With or without light
7 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 4°C Protect from light
7 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 23°C With or without light
7 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 4°C Protect from light
7 Day

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