Last update :
19/11/2024
References   References 423  
Type : Journal

Research teams : Chicago - University of Chicago Medical Center, Drug Information Services
Authors : Mansur JM, Abramowitz PW, Lerner SA, Smith RB, Townsend RJ.
Title : Stability and cost analysis of clindamycin-gentamicin admixtures given every eight hours.
Reference : Am J Hosp Pharm ; 42: 332-335. 1985

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
No comments for the degradation products

List of drugs
injectionClindamycin phosphate Antibiotic
Compatible 6 mg/ml + injectionGentamicin sulfate 0.67 mg/ml + Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 0.67 mg/ml + injectionClindamycin phosphate 6 mg/ml + Glucose 5%
Stability of mixtures
Polyvinyl chloride Glucose 5% 25°C Light
injection Clindamycin phosphate 6 mg/ml
injection Gentamicin sulfate 5 mg/ml
24 Hour

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