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References   References 3222  
Type : Journal
Web link : http://www.ajhp.org/content/68/16/1537.abstract
Research teams : Tucson - University of Arizona, Department of Pharmacy Practice & Science
Authors : Karlage K, Earhart Z, Green-Boesen K, . Myrdal PB
Title : Stability of midazolam hydrochloride injection 1-mg/mL solutions in polyvinyl chloride and polyolefin bags
Reference : Am J Health-Syst Pharm ;68:1537-1540. 2011
Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
No visual inspection
List of drugs
injectionMidazolam hydrochloride Anxiolytic
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml 20-25°C With or without light
27 Day
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml 3-4°C Protect from light
27 Day
Stability in solutions Polyolefine Glucose 5% 1 mg/ml 20-25°C With or without light
27 Day
Stability in solutions Polyolefine Glucose 5% 1 mg/ml 3-4°C Protect from light
27 Day
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