Last update :
27/11/2024
InfoStab
Infostab
List of drugs
List of drugs
Summary lists
Summary lists
Search for compatibilities
Search for compatibilities
Y-site compatibility table
Y-site compatibility table
References
References
Research teams
Research teams
valistab
valistab
Poster
Poster
Links
Links
Sponsors
Sponsors
Authors
Authors
User’s guide
User’s guide
Newsletter
Newsletter
References   References 32  
Type : Journal
Research teams : Lund - University Hospital of Lund, Hospital Pharmacy
Authors : Nyhammar EK, Johansson SG, Seiving BE.
Title : Stability of doxorubicin and vincristine sulfate in two portable infusion-pump reservoirs.
Reference : Am J Health-Syst Pharm ; 53: 1171-1173. 1996
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Degradation products quantified but not identified
List of drugs
injectionDoxorubicin hydrochloride Anticancer drug
Compatible 1,67 mg/ml + injectionVincristine sulfate 0,036 mg/ml + Sodium chloride 0,9%
injectionVincristine sulfate Anticancer drug
Compatible 0,036 mg/ml + injectionDoxorubicin hydrochloride 1,67 mg/ml + Sodium chloride 0,9%
Stability of mixtures
Polyvinyl chloride Sodium chloride 0,9% 35°C Protect from light
injection Doxorubicin hydrochloride 1,67 mg/ml
injection Vincristine sulfate 0,036 mg/ml
4 Day
Polyvinyl chloride Sodium chloride 0,9% 4°C Protect from light
injection Doxorubicin hydrochloride 1,67 mg/ml
injection Vincristine sulfate 0,036 mg/ml
7 Day
  Mentions Légales