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References   References 27  
Type : Journal
Research teams : Los Angeles - University of Southern california, School of Pharmacy
Authors : Chin A, Moon YSK, Chung KC, Gill MA.
Title : Stability of granisetron hydrochloride with dexamethasone sodium phosphate for 14 days.
Reference : Am J Health-Syst Pharm ; 53: 1174-1176. 1996
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
List of drugs
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 0.08 & 0.6 mg/ml + injectionGranisetron hydrochloride 0.01 & 0.04 mg/ml + NaCl 0,9% or Glucose 5%
injectionGranisetron hydrochloride Antiemetic
Compatible 0.01 & 0.04 mg/ml + injectionDexamethasone sodium phosphate 0.08 & 0.6 mg/ml + NaCl 0,9% or Glucose 5%
Stability of mixtures
Polyvinyl chloride NaCl 0,9% or Glucose 5% 23°C-25°C Protect from light
injection Granisetron hydrochloride 0,010 - 0,040 mg/ml
injection Dexamethasone sodium phosphate 0,080 - 0,600 mg/ml
14 Day
Polyvinyl chloride NaCl 0,9% or Glucose 5% 4°C Protect from light
injection Dexamethasone sodium phosphate 0,08 - 0,60 mg/ml
injection Granisetron hydrochloride 0,01 - 0,04 mg/ml
14 Day
  Mentions Légales