Last update :
27/11/2024
References   References 2086  
Type : Journal

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Sharley NA, Burgess NG.
Title : Stability and compatibility of alfentanil hydrochloride and morphine sulfate in poypropylene syringes.
Reference : J Pharm Pract and Res ; 33: 279-281. 2003

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
injectionAlfentanil hydrochloride Analgesic
Compatible 55 µg/ml + injectionMorphine sulfate 0,8 mg/ml + Sodium chloride 0,9%
injectionMorphine sulfate Analgesic
Compatible 0,8 mg/ml + injectionAlfentanil hydrochloride 55 µg/ml + Sodium chloride 0,9%
Stability of mixtures
Polypropylene Sodium chloride 0,9% 2-8°C Protect from light
injection Morphine sulfate 0,8 mg/ml
injection Alfentanil hydrochloride 55 µg/ml
180 Day
Polypropylene Sodium chloride 0,9% 22°C Protect from light
injection Morphine sulfate 0,8 mg/ml
injection Alfentanil hydrochloride 55 µg/ml
180 Day

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