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14/12/2024
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References 1678
Type :
Journal
Research teams :
Parkville - Monash University, Victorian College of Pharmacy
Authors :
Sitaram BR, Tsui M, Rawicki HB, Lam S, Sitaram M.
Title :
Stability and compatibility of intrathecal admixtures containing baclofen and high concentrations of morphine.
Reference :
Int J Pharm ; 153: 13-24. 1997
Level of Evidence :
Physical stability :
Chemical stability :
Other methods :
Comments :
Degradation products identified and quantified
List of drugs
Baclofen
0.2 >> 1.5 mg/ml
+
Morphine sulfate
7.5 >> 21 mg/ml
+
Morphine sulfate
7.5 >> 21 mg/ml
+
Baclofen
0.2 >> 1.5 mg/ml
+
37°C
Morphine sulfate
7,5 mg/ml
Baclofen
1,5 mg/ml
30
37°C
Morphine sulfate
15 mg/ml
Baclofen
1 mg/ml
30
37°C
Morphine sulfate
21 mg/ml
Baclofen
0,2 mg/ml
30
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