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References   References 1416  
Type : Journal
Research teams : Morgantown - West Virginia University, School of Pharmacy
Authors : Stamatakis MK, Leader G, Tracy TS.
Title : Stability of high-dose vancomycin and ceftazidime in peritoneal dialysis solutions.
Reference : Am J Health-Syst Pharm ; 56: 246-248. 1999
Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
No comments for the degradation products
List of drugs
injectionCeftazidime Antibiotic
Compatible 0.5 mg/ml + injectionVancomycin hydrochloride 1 mg/ml + Dianéal® PD2 4.25% glucose (Baxter)
injectionVancomycin hydrochloride Antibiotic
Compatible 1 mg/ml + injectionCeftazidime 0.5 mg/ml + Dianéal® PD2 4.25% glucose (Baxter)
Stability of mixtures
Polyvinyl chloride Dianéal® PD2 4.25% glucose (Baxter) 24°C
injection Ceftazidime 0,5 mg/ml
injection Vancomycin hydrochloride 1 mg/ml
24 Hour
Polyvinyl chloride Dianéal® PD2 4.25% glucose (Baxter) 37°C Light
injection Ceftazidime 0,5 mg/ml
injection Vancomycin hydrochloride 1 mg/ml
12 Hour
Polyvinyl chloride Dianéal® PD2 4.25% glucose (Baxter) 4°C Light
injection Ceftazidime 0,5 mg/ml
injection Vancomycin hydrochloride 1 mg/ml
24 Hour
Polyvinyl chloride Dianéal® PD2 1.5% glucose (Baxter) 24°C
injection Vancomycin hydrochloride 1 mg/ml
injection Ceftazidime 0,5 mg/ml
24 Hour
Polyvinyl chloride Dianéal® PD2 1.5% glucose (Baxter) 37°C
injection Ceftazidime 0,5 mg/ml
injection Vancomycin hydrochloride 1 mg/ml
12 Hour
Polyvinyl chloride Dianéal® PD2 1.5% glucose (Baxter) 4°C
injection Vancomycin hydrochloride 1 mg/ml
injection Ceftazidime 0,5 mg/ml
24 Hour
  Mentions Légales